Effectiveness and safety of 5% nicotinamide cream following cryosurgery in skin field cancerization: a randomized, double-blind, placebo-controlled clinical trial
Abstract:Individuals with multiple actinic keratoses (AKs) in the same area have an active skin field cancerization (SFC). The treatment of AKs and SFC reduces the recurrence of AKs and the appearance of squamous cell carcinomas (SCCs). Recently, oral nicotinamide (NIC) was proposed as effective in the chemoprevention of SCC and AKs, but there have been no clinical trials with topical NIC as a treatment for AKs and SFC. Thus, we conducted a prospective, randomized, double-blind, self-controlled trial to evaluate the ef… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.