Effectiveness and predictability of titanium-prepared platelet-rich fibrin for the management of multiple gingival recessions

Uzun, Bilge Cansu; Ercan, Esra; Tunalı, Mustafa

doi:10.1007/s00784-017-2211-2

Cited by 32 publications

(47 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Uzun et al ., in 2018, compared the use of T-PRF with that of connective tissue graft along with tunnel technique in the treatment of multiple gingival recession defects and found the comparable results for both techniques (93.29% and 93.22%, respectively), concluding that T-PRF can serve as an alternative to CTG. [ 13 ]…”

Section: Discussionmentioning

confidence: 99%

Pinhole surgical technique – A novel minimally invasive approach for treatment of multiple gingival recession defects: A case series

et al. 2020

View full text Add to dashboard Cite

Gingival recessions are one of the most prevalent periodontal diseases. Hypersensitivity and esthetics are the major concerns associated with recession defects. There are various treatment modalities for its management, but recently, minimally invasive techniques have gained much importance because of lower patient morbidity and comparable results when compared to conventional techniques. This case series represents a 6-month follow-up of a recently introduced pinhole surgical technique where the percentage of root coverage was found to be statistically significant.

show abstract

Section: Discussionmentioning

confidence: 99%

Pinhole surgical technique – A novel minimally invasive approach for treatment of multiple gingival recession defects: A case series

et al. 2020

View full text Add to dashboard Cite

show abstract

“…For the treatment of GRs, PRF has been used alone [22,23] or in combination with CTG [24]. Nowadays, several alternative protocols are suggested such as the horizontal centrifugation or the adding, inside the fibrin cloth, of substances such as albumin or titanium particles to increase the resorption time and the release of growth factors [25,26]. Nevertheless, this review aims to investigate and analyze the effect of the most diffused and popular second generation of platelet concentrates as L-PRF in single and multiple coronally advanced flap.…”

Section: Introductionmentioning

confidence: 99%

Platelet-Rich Fibrin in Single and Multiple Coronally Advanced Flap for Type 1 Recession: An Updated Systematic Review and Meta-Analysis

et al. 2021

View full text Add to dashboard Cite

Background and Objectives: The aim of the present systematic review and meta-analysis was to investigate the efficacy of leukocyte–platelet-rich fibrin (L-PRF) in addition to coronally advanced flap (CAF) for the treatment of both single and multiple gingival recessions (GRs) compared to the CAF alone and to the adjunct of connective tissue graft (CTG). Root coverage outcomes using platelet concentrates have gained increased interest. In particular, it has been suggested that adding L-PRF to CAF may provide further benefits in the treatment of GRs. Materials and Methods: An electronic and manual literature search was conducted to identify randomized controlled trials (RTCs) investigating root coverage outcomes with CAF + L-PRF. The outcomes of interest included mean root coverage (mRC), recession reduction, keratinized tissue width (KTW) gain, gingival thickness (GT) gain, and patient-reported outcome measures (PROms) such as pain perception and discomfort. Results: A total of 275 patients and 611 surgical sites were analyzed. L-PRF in adjunct to single CAF seems to show statistically significant results regarding clinical attachment level (CAL) with a weighted means (WM) 0.43 95% CI (−0.04,0.91), p < 0.0001, GT (WM 0.17 95% CI (−0.02,0.36), p < 0.0001, and mRC (WM 13.95 95% CI (−1.99,29.88) p < 0.0001, compared to single CAF alone. Interesting results were obtained from the adjunct of PRF to multiple CAF with respect to multiple CAF alone with an increase in the mRC WM 0.07 95% CI (−30.22,30.35), p = 0.0001, and PPD change WM 0.26 95% CI (−0.06,0.58), p < 00001. On the other hand, no statistically significant data were obtained when L-PRF was added to single or multiple CAF combined with CTG according to the included outcomes such as mRC (p = 0.03 overall). Conclusions: L-PRF is a valid alternative to CAF alone. L-PRF compared to CTG in single and multiple CAF showed statistically significant results regarding pain perception and discomfort PROms (p < 0.0001). However, CTG remains the gold standard for treating gingival recession.

show abstract

“…For this reason, through several pathways, horizontal and/or vertical cross-infection may develop between the root canal and the periodontal tissue, including apical foramen, lateral and accessory canals, dentinal tubules, pal-to its thicker fibrin texture and longer resorption time in the tissues (10). Various treatment options including gingival recessions, IBDs, sinus lifting procedure, and periodontal healing have made use of T-PRF (11,12). In the literature, no studies comparing the efficacy of GTR and T-PRF in the treatment of endo-perio lesions have been found.…”

Section: Introductionmentioning

confidence: 99%

Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trial

Ustaoğlu

Aydın²,

Özelçi³

2020

Med Oral

View full text Add to dashboard Cite

Background: Titanium-prepared platelet rich fibrin (T-PRF) is an autologous hemo-component with a high concentration of platelets that also incorporates leukocytes, and growth factors into the dense fibrin matrix and can be used as a healing biomaterial. This study assesses the adjunctive use of T-PRF in intrabony defects (IBDs) with open flap debridement (OFD) in comparison with guided tissue regeneration (GTR) as a gold standard and OFD alone as a control. Material and Methods: A total of 45 patients (15 per group) were randomized as either T-PRF (test group), GTR (test group), or OFD alone (control group) sites. Probing depth (PD), clinical attachment level (CAL), and IBD were recorded. The radiographic depth of IBD was also measured. Primary outcomes assessed were changes in PD, CAL, and radiographic IBD that were assessed at the beginning and nine months later. Results: The PRF and GTR group showed significant improvement in clinical parameters compared with the OFD alone (control group) at nine months. While there were no significant differences in PD and CAL between test groups (T-PRF and GTR groups), the significant difference was found in radiographic IBD depth. Conclusion: T-PRF may give similar successful results as GTR in the treatment of IBDs with endo-perio lesions.

show abstract

Effectiveness and predictability of titanium-prepared platelet-rich fibrin for the management of multiple gingival recessions

Abstract: T-PRF can serve as a good autogenous alternative to CTG, which is the gold standard for root coverage.

Cited by 32 publications

References 37 publications

Pinhole surgical technique – A novel minimally invasive approach for treatment of multiple gingival recession defects: A case series

Pinhole surgical technique – A novel minimally invasive approach for treatment of multiple gingival recession defects: A case series

Platelet-Rich Fibrin in Single and Multiple Coronally Advanced Flap for Type 1 Recession: An Updated Systematic Review and Meta-Analysis

Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trial

Contact Info

Product

Resources

About