Effectiveness and cost-effectiveness of a digital health intervention to support patients with colorectal cancer prepare for and recover from surgery: study protocol of the RecoverEsupport randomised controlled trial

Wyse, Rebecca; Smith, Stephen R.; Zucca, Alison; Fakes, Kristy; Mansfield, Elise; Johnston, Sally-Ann; Robinson, Sancha; Oldmeadow, Christopher; Reeves, Penny; Carey, Mariko; Norton, Grace; Sanson‐Fisher, Rob

doi:10.1136/bmjopen-2022-067150

Cited by 2 publications

References 33 publications

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The effect on response rates of adding a QR code to patient consent forms for qualitative research with cancer patients: A Pilot Randomised Controlled Study (Preprint)

Wyse,

Forbes,

Norton

et al. 2024

Preprint

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BACKGROUND The successful conduct of health and medical research is largely dependent on participant recruitment. Effective, yet inexpensive methods of increasing response rates for all types of research are required. Quick Response (QR) codes are now commonplace, and despite having been extensively used to recruit study participants, a search of the literature failed to reveal any randomised trial investigating the effect of adding a QR code on qualitative research response rates. OBJECTIVE To collect data regarding the impact of the addition of a QR code to a patient consent form for a qualitative research study on cancer patients’ rates of response, consent and decline, and the average time taken to respond. METHODS This was a pilot randomised controlled trial (RCT) embedded within a qualitative research study. Forty eligible patients received a recruitment pack for the qualitative study which included an information statement, a consent form, and an addressed, stamped envelope to return their consent form. Patients were randomised in a 1:1 ratio to the control (standard recruitment pack only) or intervention group (standard recruitment pack including modified consent form with a QR code). RESULTS Twenty-seven out of 40 patients responded to the consent form. A lower proportion of the QR code group (60%) responded, compared to 75% of the standard recruitment group. However, a higher proportion of the QR group consented (35%) compared to the standard recruitment group (20%), and a lower proportion of the QR group declined (25%) relative to the standard recruitment group (55%). The mean response time of the QR code group was 16 days compared to 19 days for the standard recruitment group. None of the age-adjusted analyses were statistically significant. CONCLUSIONS This trial provides useful preliminary data on the potential impact of QR codes on patient response rates to invitations to participate in qualitative research and can be used to inform a fully powered randomised control trial.

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The effect on response rates of adding a QR code to patient consent forms for qualitative research with cancer patients: A Pilot Randomised Controlled Study (Preprint)

Wyse,

Forbes,

Norton

et al. 2024

Preprint

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The impact of skeletal muscle index at the third lumbar spine on nosocomial deterioration and short-term prognosis in acute pancreatitis: a retrospective observational study

Lin,

Zhang,

Wang

et al. 2024

PeerJ

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Objective To investigate the impact of the third lumbar skeletal muscle index (L3-SMI) assessed by CT on the in-hospital severity and short-term prognosis of acute pancreatitis. Methods A total of 224 patients with severe acute pancreatitis admitted to Yantaishan Hospital from January 2021 to June 2022 were selected as the subjects. Based on the in-hospital treatment outcomes, they were divided into a mortality group of 59 cases as well as a survival group of 165 cases. Upon admission, general information such as the Acute Physiology and Chronic Health Evaluation II (APACHE II) score, along with the abdominal CT images of each patient, were analyzed. The L3-SMI was calculated, and the Modified CT Severity Index (MCTSI) and Balthazar CT grade were used to assess the severity of in-hospital complications of acute pancreatitis. The evaluation value of L3-SMI for the prognosis of severe acute pancreatitis was analyzed, as well as the factors influencing the prognosis of severe acute pancreatitis. Results No statistically significant differences in gender, age, BMI, etiology, duration of anti-inflammatory drug use, and proportion of surgical patients between the survival and mortality groups were observed. But the mortality group showed higher proportions of patients with an elevated APACHE II score upon admission, mechanical ventilation, and renal replacement therapy, compared to the survival group, with statistically significant differences (P < 0.001). Furthermore, the mortality group had higher MCTSI scores (6.42 ± 0.69) and Balthazar CT grades (3.78 ± 0.45) than the survival group, with statistically significant differences (P < 0.001). The mortality group also had a lower L3-SMI (39.68 ± 3.25) compared to the survival group (42.71 ± 4.28), with statistically significant differences (P < 0.001). L3-SMI exhibited a negative correlation with MCTSI scores and Balthazar CT grades (r = −0.889, −0.790, P < 0.001). Logistic regression analysis, with mortality of acute pancreatitis patients as the dependent variable and MCTSI scores, Balthazar CT grades, L3-SMI, APACHE II score upon admission, mechanical ventilation, and renal replacement therapy as independent variables, revealed that MCTSI scores and L3-SMI were risk factors for mortality in acute pancreatitis patients (P < 0.001). Logistic regression analysis using the same variables confirmed that all these factors were risk factors for mortality in acute pancreatitis patients. Conclusion This study confirmed that diagnosing muscle depletion using L3-SMI is a valuable radiological parameter for predicting in-hospital severity and short-term prognosis in patients with acute pancreatitis.

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Effectiveness and cost-effectiveness of a digital health intervention to support patients with colorectal cancer prepare for and recover from surgery: study protocol of the RecoverEsupport randomised controlled trial

Cited by 2 publications

References 33 publications

The effect on response rates of adding a QR code to patient consent forms for qualitative research with cancer patients: A Pilot Randomised Controlled Study (Preprint)

The effect on response rates of adding a QR code to patient consent forms for qualitative research with cancer patients: A Pilot Randomised Controlled Study (Preprint)

The impact of skeletal muscle index at the third lumbar spine on nosocomial deterioration and short-term prognosis in acute pancreatitis: a retrospective observational study

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