Effective treatment of folliculitis decalvans using selected antimicrobial agents

Abstract

Folliculitis Decalvans (FD) is a rare neutrophilic infammation of the scalp characterized by painful, recurrent purulent follicular exudation resulting in primary cicatricial alopecia. However, unclear etiology makes FD treatment a difficult task. A wide variety of topical and systemic agents have been tried previously, with varied results. We present here a case series report of a set of 13 patients with FD on antimicrobial therapy.

Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-standing Cases

“…4,11,12 Most patients were Caucasian, which is in contrast to some studies that found this disease mostly in patients of African ethnicity, although this finding could be due to the population bias of this particular hospital of having mostly Caucasian patients. 3,8 The majority of patients in this study were young to middle-aged adults.…”

Severe Infliximab-Induced Alopecia and Scalp Psoriasis in a Woman with Crohn’s Disease: Dramatic Improvement after Drug Discontinuation and Treatment with Adjuvant Systemic and Topical Therapies

“…Alternatively, it is possible that the biopsy was obtained from a non-representative area of the scalp, and the true diagnosis was tumor necrosis factor alpha-induced psoriasis complicated by an overlying cellulitis. Minocycline was initially selected as a first-line therapy for folliculitis decalvans [16]. However, it likely aided in resolving an overlying cellulitis or impetiginization and may have helped to decrease local dermal inflammation.…”

A comparative study of treatment modalities in female androgenetic alopecia

“…According to Zhang X, et al study serum ferritin level lower than required was seen in 25% of female patients. 14 Supplementing the diet with biotin is unlikely to harm a patient, and the importance of iron supplements in irondeficient women with hair loss has been demonstrated.…”