Effective Strategies for Recruiting Families Ascertained Through Alcoholic Probands

Seaton, Kimberly L.; Cornell, Jodi L.; Wilhelmsen, Kirk C.; Vieten, Cassandra

doi:10.1097/01.alc.0000107200.88229.57

Cited by 19 publications

(25 citation statements)

References 14 publications

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“…Computer use may not be equal across demographic groups, possibly creating biased samples (Etter & Perneger, 2001;Scholle et al, 2000). Finally, Internet recruitment may not be an effective tool for studies recruiting locally, since it may be harder to target a specific geographic area (Seaton, Cornell, Wilhelmsen, & Vieten, 2004). The Internet may be more successful when used in conjunction with traditional recruitment methods.…”

Section: Discussionmentioning

confidence: 99%

Cost effectiveness of recruitment methods in an obesity prevention trial for young children

Robinson

Fuerch

Winiewicz

et al. 2007

Preventive Medicine

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Section: Discussionmentioning

confidence: 99%

Cost effectiveness of recruitment methods in an obesity prevention trial for young children

Robinson

Fuerch

Winiewicz

et al. 2007

Preventive Medicine

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“…Purchase of such demographically defined mailing or telephone lists has become a more frequent strategy for recruiting participants across a wide range of research domains, including infant development (Kraebel & Gerhardstein 2006), alcoholism (Seaton et al, 2004), adolescent gambling (Winters et al, 1993), cancer prevention (Bowen et al, 2004), and health promotion (Hays et al, 2003). Information provided by the company indicated that the phone numbers were compiled from the following sources: Lamaze classes, baby registries, mail order purchases, magazine subscriptions, and questionnaire data.…”

Section: Recruitment Strategies and Costsmentioning

confidence: 99%

Clinical trials and tribulations: Lessons learned from recruiting pregnant ex-smokers for relapse prevention

Lopez

Simmons

Quinn

et al. 2008

CNTR

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The development of smoking cessation and relapse-prevention interventions for pregnant and postpartum women is a public health priority. However, researchers have consistently reported substantial difficulty in accruing this population into clinical trials. The problem is particularly acute for relapse-prevention studies, which must recruit women who have already quit smoking because of their pregnancy. Although an important target for tobacco control efforts, these individuals represent an extremely small subgroup of the general population. This paper describes multiple recruitment strategies utilized for a clinical trial of a self-help relapse-prevention program for pregnant women. The effectiveness of the strategies and the direct expense per participant accrued are provided. A proactive recruitment strategy (telephoning women whose phone numbers were purchased from a marketing firm) was ultimately much more successful than a variety of reactive strategies (advertisement, press releases, direct mail, web placement, healthcare provider outreach). There were few differences between proactively and reactively recruited participants on baseline variables; the primary difference was that the former had smoked fewer cigarettes per day and reported lower nicotine dependence prior to quitting. Strengths and limitations of the recruitment strategies are discussed.The risks associated with smoking during pregnancy are well established and highly publicized (Britton, 1998; CDC, 1995; United States Department of Health and Human Services [USDHHS], 1990[USDHHS], , 2001. Consequently, an increasing proportion of women (estimates range from 15% to 60%) spontaneously quit smoking immediately prior to or during their pregnancy (Ershoff et al., 2000;Morasco et al., 2006). However, maintenance of tobacco abstinence among pregnant and postpartum women remains a challenge. Smoking relapse rates among pregnant and postpartum women range from 70-80%, with approximately half of these women resuming smoking within the first twelve weeks postdelivery (Fingerhut et al., 1990;Ockene, 1993;Polanska et al., 2005; USDHHS, 2001). Postpartum smoking exposes the infant to environmental tobacco smoke, which is associated with a range of health problems in children including middle ear infection, asthma, sudden infant death syndrome, behavioral problems, and developmental delays (Charlton, 1994; USDHHS, 2006). Of course, by resuming smoking, the mother also reexposes herself to the myriad health risks associated with tobacco use. Given the high rate of self-quitting among pregnant smokers, as well as the success of interventions designed to motivate pregnant women to quit smoking (Melvin et al., 2000), pregnancy and the early postpartum period appear to offer unique opportunities to provide smoking relapseprevention interventions, although such efforts have met with at best modest success to date (Mullen, 2004).Recruiting participants for clinical trials can be challenging in general (e.g., Harris et al., 2003;Ross et al., 1999), and t...

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“…No inclusion/exclusion criteria were applied aside from the ability to respond to the telephone interview and complete the questionnaires. The details of recruitment of all participants have been previously published [see Seaton et al, 2004; Veiten et al, 2004]. …”

Section: Methodsmentioning

confidence: 99%

“…Test-retest and inter-rater reliability for clinical data have been shown to be very good [Vieten et al, 2004]. Design, methods, recruitment strategies and sample demographics of the UCSF Family Alcoholism Study have been presented previously [see Seaton et al, 2004; Vieten et al, 2004], along with intrafamilial correlations for primary diagnostic phenotypes.…”

Section: Introductionmentioning

confidence: 99%

Linkage analyses of cannabis dependence, craving, and withdrawal in the San Francisco family study

Ehlers

Gizer

Vieten

et al. 2009

American J of Med Genetics Pt B

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Cannabis is the most widely used illicit drug in the United States. There is ample evidence that cannabis use has a heritable component, yet the genes underlying cannabis use disorders are yet to be completely identified. This study's aims were to map susceptibility loci for cannabis use and dependence and two narrower cannabis-related phenotypes of "craving" and "withdrawal" using a family study design. Participants were 2524 adults participating in the University of California San Francisco (UCSF) Family Alcoholism Study. DSM-IV diagnoses of cannabis dependence, as well as indices of cannabis craving and withdrawal, were obtained using a modified version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). Genotypes were determined for a panel of 791 microsatellite polymorphisms. Multipoint variance component LOD scores were obtained using SOLAR. Genome-wide significance for linkage (LOD > 3.0) was not found for the DSM-IV cannabis dependence diagnosis, however, linkage analyses of cannabis "craving" and the cannabis withdrawal symptom of "nervous, tense, restless or irritable" revealed five sites with LOD scores over 3.0 on chromosomes 1, 3, 6, 7, 9. These results identify new regions of the genome associated with cannabis use phenotypes as well as corroborate the importance of several chromosome regions highlighted in previous linkage analyses for other substance dependence phenotypes.

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Effective Strategies for Recruiting Families Ascertained Through Alcoholic Probands

Abstract: Results provide insight into successful strategies for recruiting large numbers of participants and their family members selected for a condition associated with a social stigma.

Cited by 19 publications

References 14 publications

Cost effectiveness of recruitment methods in an obesity prevention trial for young children

Cost effectiveness of recruitment methods in an obesity prevention trial for young children

Clinical trials and tribulations: Lessons learned from recruiting pregnant ex-smokers for relapse prevention

Linkage analyses of cannabis dependence, craving, and withdrawal in the San Francisco family study

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