Effective laboratory Evaluation of Thyroid Status

Thyroid Hormones and Cytogenetic Outcomes in Backpack Sprayers Using Ethylenebis(dithiocarbamate) (EBDC) Fungicides in Mexico

“…Most of these workers had been exposed to EBDCs and ETU for several weeks or months at the time of testing; homeostasis with normal T4 but elevated TSH might be expected after several weeks of exposure (24). The effect on TSH is consistent with animal data (1).…”

Risk for Fracture in Women with Low Serum Levels of Thyroid-Stimulating Hormone

“…Levels of TSH were measured only once, and some women may have had transiently low levels; however, a second TSH measurement would probably only have strengthened the observed association between low TSH and fracture. In addition, we cannot rule out the possibility that a small number of women in our cohort had low TSH levels as a result of severe medical or psychiatric illness (51), but the adverse effects of low TSH persisted after adjustment for selfrated health. Thyroid-stimulating hormone was measured in sera that had been archived for approximately 6 to 8 years at Ϫ190°C; although the effects of long-term storage at these temperatures have not been studied, the TSH levels reported in this study were similar to those in other similar older cohorts (52).…”

Hypothyroidism and Thyroiditis after Therapy for Hodgkin’s Disease

“…Free thyroxin (FT4) was measured with the competitive luminescent immunoassay (LIA-mat FT4) using the free triiodothyronine (FT3) Imx Free T3 assay, which is based on the microparticulated enzyme immunoassay (Abbot) [25, 26]. Using the above methods, normal ranges should be as follows: sTSH: 0.3–3.0 mlU/ml, FT3: 2.6– 5.4 pmol/l, FT4: 7.22–23.2 pmol/l.…”