Sergeyev research interests include high energy lasers propagation through the turbulent atmosphere, developing advanced control algorithms for wavefront sensing and mitigating effects of the turbulent atmosphere, digital inline holography, digital signal processing, and laser spectroscopy. He is also involved in developing new eye-tracking experimental techniques for extracting 3-D shape of the object from the movement of human eyes. Dr. Sergeyev is a member of American Society for Engineering Education (ASEE) and actively involved in promoting engineering education.