Effective Inhibition of Newly Emerged A/H7N9 Virus with Oligonucleotides Targeted to Conserved Regions of the Virus Genome

Antisense oligonucleotides against herpes simplex virus

“…We took into account the results of our previous work, which demonstrated the success of this approach when using nanocomposites based on titanium dioxide and aminosilanol nanoparticles to deliver oligonucleotides to eukaryotic cells and suppress the replication of influenza A virus in vitro [7][8][9] and in vivo [10]. Nanoparticles act as carriers of oligonucleotides and, in addition, protect them against nucleases.…”