Effective follow-up for recurrence or a second primary cancer in patients with early gastric cancer

Ikeda, Yoichi; Saku, Motonori; Kishihara, Fumiaki; Maehara, Yoshihiko

doi:10.1002/bjs.4758

Cited by 80 publications

(52 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, it showed older age was significantly related to the progress of GC recurrent. However, it is not in agreement with previous study which reported age at diagnosis as an independent factor for recurrence of early gastric cancer (Ikeda et al, 2005). Marrelli et al, also showed the age at diagnosis as a significant risk factor affected on the GC recurrence (Marrelli et al, 2005).…”

Section: 2639 Gastric Cancer Recurrence and Associated Factors In Irancontrasting

confidence: 61%

Prediction of Time to Recurrence and Influencing Factors for Gastric Cancer in Iran

Roshanaei

Ghannad²,

Safari³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Background: The patterns of gastric cancer recurrence vary across societies. We designed the current study in an attempt to evaluate and reveal the outbreak of the recurrence patterns of gastric cancer and also prediction of time to recurrence and its effected factors in Iran. Conclusions: We found that pathologic stage, tumor grade and tumor site significantly affect on the recurrence of GC which has a high positive prognostic value and might be functional for better follow-up and selecting the patients at risk. We also showed time to recurrence to be an important factor for follow-up of patients.

show abstract

Section: 2639 Gastric Cancer Recurrence and Associated Factors In Irancontrasting

confidence: 61%

Prediction of Time to Recurrence and Influencing Factors for Gastric Cancer in Iran

Roshanaei

Ghannad²,

Safari³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…In these two patients, one patient underwent total gastrectomy after endoscopic treatment, and endoscopic treatment continues in the other patient. The frequency of multicentric gastric cancer is estimated overall as 2-19% (Arai et al 1992;Suzuki et al 1995), and rate of metachronous gastric cancer after gastrectomy for early gastric cancer is estimated to be 0.5-3% (Ikeda et al 2005;Nozaki et al 2010). Results in the present study indicate a predisposition to multicentric gastric carcinogenesis in patients with FAP.…”

Section: Discussionmentioning

confidence: 47%

Clinical Characteristics of Gastric Cancer in Patients with Familial Adenomatous Polyposis

Shibata

Ogawa

Miura

et al. 2013

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

Familial adenomatous polyposis is an autosomal dominant hereditary disease leading to the development of numerous colorectal polyps with malignant potential. Extra-colonic neoplasms are observed often in patients with familial adenomatous polyposis, but clinical characteristics of gastric cancer associated with familial adenomatous polyposis are not well understood. We studied the clinical characteristics of five Japanese patients who developed gastric cancer after undergoing colectomy for familial adenomatous polyposis. Gastric cancer was found on gastroduodenal endoscopy performed during postoperative follow-up in all five patients. Mean ages at the time of colectomy and at the time of diagnosis of gastric cancer were 39.2 and 58 years, respectively. Importantly, gastric fundic gland polyps were undetectable in these five patients. The mean duration between colectomy and diagnosis of gastric cancer was more than 20 years in three of five patients (mean: 19 years and 1 month). Cancers were multiple in three of five patients. Two patients developed metachronous gastric cancer in the gastric remnant. All five patients presented with well to moderately differentiated adenocarcinoma; four of the five patients were stage IA. Characteristics of the gastric cancer with familial adenomatous polyposis include a long duration between occurrence of gastric cancer and colectomy, metachronous cancers, multicentric lesions, and a high rate of well to moderately differentiated adenocarcinoma. Long-term and periodic gastroduodenal surveillance endoscopy is recommended for patients with FAP who underwent colectomy.

show abstract

“…When partial gastrectomy is performed for removal of the primary cancer, the metachronous cancer can be called remnant gastric cancer [1][2][3][4]. It has been reported that the incidence of metachronous gastric cancer after partial gastrectomy for early gastric cancer is 0.6-3.0 % [1,[4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Incidence of metachronous gastric cancer in the remnant stomach after synchronous multiple cancer surgery

et al. 2013

View full text Add to dashboard Cite

Background In the preoperative evaluation for gastric cancer, high-resolution endoscopic technologies allow us to detect small accessory lesions. However, it is not known if the gastric remnant after partial gastrectomy for synchronous multiple gastric cancers has a greater risk for metachronous cancer. The purpose of this study was to determine the incidence of metachronous cancer in this patient subset compared with that after solitary cancer surgery. Methods Data on a consecutive series of 1,281 patients gastrectomized for early gastric cancer from 1991 to 2007 were analyzed retrospectively. The 715 gastric remnants after distal gastrectomy were periodically surveyed by endoscopic examination in Shikoku Cancer Center. Among those surveyed cases, 642 patients were pathologically diagnosed with solitary lesion (SO group) and 73 patients with synchronous multiple lesions (MU group) at the time of the initial surgery. Results In the follow-up period, 15 patients in the SO group and 3 patients in the MU group were diagnosed as having metachronous cancer in the gastric remnant. The cumulative 4-year incidence rate was 1.9 % in the SO group and 5.5 % in the MU group. The difference did not reach the significant level by the log-rank test. ConclusionsThe incidence of metachronous cancer is higher after multiple cancer surgery; however, the difference is not statistically significant.

show abstract

Effective follow-up for recurrence or a second primary cancer in patients with early gastric cancer

Abstract: Clinicopathological features of patients with early gastric cancer can be used to identify those most at risk of developing either recurrence or a second primary cancer.

Cited by 80 publications

References 16 publications

Prediction of Time to Recurrence and Influencing Factors for Gastric Cancer in Iran

Prediction of Time to Recurrence and Influencing Factors for Gastric Cancer in Iran

Clinical Characteristics of Gastric Cancer in Patients with Familial Adenomatous Polyposis

Incidence of metachronous gastric cancer in the remnant stomach after synchronous multiple cancer surgery

Contact Info

Product

Resources

About