Effective Diagnostic Marker for Serodiagnosis of Toxoplasma gondii Infection: New Developments and Perspectives

Abstract

Toxoplasmosis is a prevalent parasitic infection caused by an obligate intracellular parasite Toxoplasma gondii. Various methods have been established in the laboratory diagnosis of toxoplasmosis. Among these methods, serological tests are common and provide satisfactory results. However, producing reliable reagents and standard antigen remains difficult and expensive. Replacing native antigens in all current diagnostic kits with standard and reliable reagents are speculated to achieve more sensitive and specific detection that can significantly improve the assay performance. This review provides updated data on toxoplasmosis serodiagnosis. It focuses on the recent trends of producing reliable and standard antigens that have been used in the serological tests of toxoplasmosis, as well as the future direction in this field.

Neurotropic Parasitic Infections Associated With Psychiatric Disorders: A Review Article

“…1-Toxoplasmosis: Toxoplasmosis is a highly prevalent zoonosis. Immunocompromissed and congenitally infected patients were found to be particularly vulnerable to diseafatalities (Elsheikha et al, 2009;Mohamed and Hajissa, 2016). Its causative agent, T. gondii, is an obligatory intracellular eukaryotic protozoan parasite (Tyebji et al, 2019).…”