Effective delivery and selective insecticidal activity of double-stranded RNA via complexation with diblock copolymer varies with polymer block composition
Abstract:Chemical insecticides are an important tool to control damaging pest infestations. However, lack of species specificity, the rise of resistance to these pesticides and the demand for biological alternatives with improved ecotoxicity profiles means that chemicals with new mode-of-actions are required. RNA interference (RNAi)-based strategies that use double-stranded RNA (dsRNA) as a species-specific bio-insecticide offer an exquisite solution that addresses these issues. Many species, such as the fruit pest Dro… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.