Effective connectivities of cortical regions for top-down face processing: A Dynamic Causal Modeling study

Li, Jun; Liu, Jiangang; Liang, Jimin; Zhang, Hongchuan; Zhao, Jing; Rieth, Cory A.; Huber, David E.; Li, Wu; Shi, Guangming; Lin, Aiming; Tian, Jie; Lee, Kang

doi:10.1016/j.brainres.2010.04.044

Cited by 43 publications

(42 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, these data support the proposed right hemispheric dominance in face perception (Murphy et al 2003). faces perception network and represents facial components, so is essential for facial identity (Li et al 2010;Pitcher et al 2011). Complementarily, the posterior portion of the middle temporal gyrus has been associated with the perception of facial expressions (Hein and Knight 2008;Said et al 2010).…”

Section: Discussionsupporting

confidence: 77%

See 1 more Smart Citation

Is a neutral expression also a neutral stimulus? A study with functional magnetic resonance

et al. 2013

View full text Add to dashboard Cite

Esta es la versión de autor del artículo publicado en: This is an author produced version of a paper published in: El acceso a la versión del editor puede requerir la suscripción del recurso Access to the published version may require subscription AbstractAlthough neutral faces do not initially convey an explicit emotional message, it has been found that individuals tend to assign them an affective content. Moreover, previous research has shown that affective judgments are mediated by the task they have to perform. Using functional Magnetic Resonance Imaging in 21 healthy participants, we focus this study on the cerebral activity patterns triggered by neutral and emotional faces in two different tasks (social or gender judgments). Results obtained, using conjunction analyses, indicated that viewing both emotional and neutral faces evokes activity in several similar brain areas indicating a common neural substrate. Moreover, neutral faces specifically elicit activation of cerebellum, frontal and temporal areas while emotional faces involve the cuneus, anterior cingulated gyrus, medial orbitofrontal cortex, posterior superior temporal gyrus, precentral/postcentral gyrus and insula. The task selected was also found to influence brain activity, in that the social task recruited frontal areas while the gender task involved the posterior cingulated, inferior parietal lobule and middle temporal gyrus to a greater extent. Specifically, in the social task viewing neutral faces was associated with longer reaction times and increased activity of left dorsolateral frontal cortex compared with viewing facial expressions of emotions. In contrast, in the same task emotional expressions distinctively activated the left amygdale. The results are discussed taking into consideration the fact that, like other facial expressions, neutral expressions are usually assigned some emotional significance. However, neutral faces evoke a greater activation of circuits probably involved in more elaborate cognitive processing.

show abstract

Section: Discussionsupporting

confidence: 77%

“…THE OFC has also been attributed a crucial role in the top-down processing of faces regulating the activities of the OFA and the fusiform face area (FFA). This top-down face processing is required to interpret ambiguous faces stimuli, imagined face or to detect impoverished face stimuli (Li et al, 2010).…”

Section: Neutral and Emotional Activationmentioning

confidence: 99%

Is a neutral expression also a neutral stimulus? A study with functional magnetic resonance

et al. 2013

View full text Add to dashboard Cite

show abstract

“…For example, prosopagnosic patients, with lesions that affect the OFA, continue to show activity in the FFA (Rossion et al 2003;Steeves et al 2006). We also found evidence for a functional connection between the OFA and STS and between the FFA and STS (see also Fairhall and Ishai 2007;Li et al 2010;TurkBrowne et al 2010). However, the correlations between the residual time courses of the OFA-STS and FFA-STS were not significantly increased when participants viewed faces compared with other non-face objects.…”

Section: Connectivity Between Face-selective Regionsmentioning

confidence: 77%

Intra- and interhemispheric connectivity between face-selective regions in the human brain

Davies‐Thompson

Andrews

2012

Journal of Neurophysiology

View full text Add to dashboard Cite

show abstract

“…We limited the number of models defined by bilinear approximation (Friston et al, 2003). We did not consider nonlinear approach and any other complex models since simple models are preferred to complex models (Friston, 2011;Penny et al, 2004) to maintain the balance between accuracy and complexity (Dima et al, 2011;Herrington et al, 2011;Li et al, 2010;Pitt and Myung, 2002;Stephan et al, 2010).…”

Section: Figmentioning

confidence: 99%

“…The co-ordinates were obtained from the second level analysis at p < 0.005 (FDR) using xjView8 (www.alivelearn.net/ xjview8/) by combining only correct trials for both happy (clear and noisy) and angry (clear and noisy) emotions in a single F-contrast versus rest. For each individual participant, the participant specific maxima were constrained to lie within twice the width of Gaussian smoothing kernel used (Li et al, 2010). In two participants, activation clusters did not meet the above criterion and we discarded them for the DCM analysis.…”

Section: Figmentioning

confidence: 99%

Amygdala Mediated Connectivity in Perceptual Decision-Making of Emotional Facial Expressions

et al. 2013

View full text Add to dashboard Cite

Recognizing emotional facial expressions is a part of perceptual decision-making processes in the brain. Arriving at a decision for the brain becomes more difficult when available sensory information is limited or ambiguous. We used clear and noisy pictures with happy and angry emotional expressions and asked 32 participants to categorize these pictures based on emotions. There were significant differences in behavioral accuracy and reaction time between the decisions of clear and noisy images. The functional magnetic resonance imaging activations showed that the inferior occipital gyrus (IOG), fusiform gyrus (FG), amygdala (AMG) and ventrolateral prefrontal cortex (VPFC) along with other regions were active during the perceptual decision-making process. Using dynamic causal modeling analysis, we obtained three important results. First, from Bayesian model selection (BMS) approach, we found that the feed-forward network activity was enhanced during the processing of clear and noisy happy faces more than during the processing of clear angry faces. The AMG mediated this feed-forward connectivity in processing of clear and noisy happy faces, whereas the AMG mediation was absent in case of clear angry faces. However, this network activity was enhanced in case of noisy angry faces. Second, connectivity parameters obtained from Bayesian model averaging (BMA) suggested that the forward connectivity dominated over the backward connectivity during such processes. Third, based on the BMA parameters, we found that the easier tasks modulated effective connectivity from IOG to FG, AMG, and VPFC more than the difficult tasks did. These findings suggest that both parallel and hierarchical brain processes are at work during perceptual decision-making of negative, positive, unambiguous and ambiguous emotional expressions, but the AMG-mediated feed-forward network plays a dominant role in such decisions.

show abstract

Effective connectivities of cortical regions for top-down face processing: A Dynamic Causal Modeling study

Cited by 43 publications

References 51 publications

Is a neutral expression also a neutral stimulus? A study with functional magnetic resonance

Is a neutral expression also a neutral stimulus? A study with functional magnetic resonance

Intra- and interhemispheric connectivity between face-selective regions in the human brain

Amygdala Mediated Connectivity in Perceptual Decision-Making of Emotional Facial Expressions

Contact Info

Product

Resources

About