Effect on the adherence to concomitant medications after initiation of treatment with direct-acting antiviral agents against hepatitis C virus

Sustained virological response after treatment with direct‐acting antivirals can help immune reconstitution in HIV‐HCV coinfected patients even in case of persistent HIV low‐level viremia

“…The choice of SVR12 in the present study instead of a 24‐week interval from anti‐HCV treatment start may justify the different result and reinforce our hypothesis even though we cannot exclude that some patients could have a detectable but not quantifiable HIV‐RNA if retested. However, a higher adherence to ART during DAA treatment should be taken into account as well 20 . We are aware that only slight differences in viroimmunological parameters were reported but, on the other hand, the patients included were immunocompetent and with an ongoing antiretroviral treatment, even if with a different level of virological suppression.…”

“…However, a higher adherence to ART during DAA treatment should be taken into account as well. 20 We are aware that only slight differences in viroimmunological parameters were reported but, on the other hand, the patients included were immunocompetent and with an ongoing antiretroviral treatment, even if with a different level of virological suppression.…”