Effect on mouse peritoneal macrophages of orally administered very high dilutions of silica

Davenas, Elisabeth; Poitevin, Bernard; Benveniste, Jacques

doi:10.1016/0014-2999(87)90680-7

Cited by 96 publications

(39 citation statements)

References 16 publications

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“…Less known are the experiments performed by Benveniste's team after publication of the controversial article in 1988. Thus, a large series of blind experiments with the same basophil model was performed under the supervision of statisticians and statistically significant results were obtained in favor of the effects of high dilutions confirming both the results of 1988 in Nature and other results previously published with the same biological model (Davenas et al, 1987;Benveniste et al, 1991). Nevertheless, Benveniste abandoned basophils and searched for other models that were less disputed.…”

supporting

confidence: 67%

Quantum-like Interferences of Experimenter's Mental States: Application to “Paradoxical” Results in Physiology

Beauvais¹

2013

Neuroquantology

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Objectives: "Memory of water" experiments (also known as Benveniste's experiments) were the source of a famous controversy in the contemporary history of sciences. We recently proposed a formal framework devoid of any reference to "memory of water" to describe these disputed experiments. In this framework, the results of Benveniste's experiments are seen as the consequence of quantum-like interferences of cognitive states. Design: In the present article, we describe retrospectively a series of experiments in physiology (Langendorff preparation) performed in 1993 by Benveniste's team for a public demonstration. These experiments aimed at demonstrating "electronic transmission of molecular information" from protein solution (ovalbumin) to naïve water. The experiments were closely controlled and blinded by participants not belonging to Benveniste's team. Results: The number of samples associated with signal (change of coronary flow of isolated rodent heart) was as expected; this was an essential result since, according to mainstream science, no effect at all was supposed to occur. However, besides coherent correlations, some results were paradoxical and remained incomprehensible in a classical framework. However, using a quantum-like model, the probabilities of the different outcomes could be calculated according to the different experimental contexts. Conclusion: In this reassessment of an historical series of "memory of water" experiments, quantum-like probabilities allowed modeling these controversial experiments that remained unexplained in a classical frame and no logical paradox persisted. All the features of Benveniste's experiments were taken into account with this model, which did not involve the hypothesis of "memory of water" or any other "local" explanation.

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supporting

confidence: 67%

Quantum-like Interferences of Experimenter's Mental States: Application to “Paradoxical” Results in Physiology

Beauvais¹

2013

Neuroquantology

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“…While pharmacological studies have been published recently (Cazin et al, 1987;Davenas et al, 1987Davenas et al, , 1988, conventional clinical trials published in the non-homoeopathic literature are exceptional (Reilly et al, 1986). Reviews : Scofield, 1984 stress the weakness of most homoeopathy trials and underline the methodological difficulties of such an enterprise.…”

Section: Discussionmentioning

confidence: 99%

A controlled evaluation of a homoeopathic preparation in the treatment of influenza‐like syndromes.

Ferley

Zmirou

D'Adhemar

et al. 1989

Brit J Clinical Pharma

104

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1. A controlled clinical trial was conducted to assess the effectiveness of a homoeopathic preparation in the treatment of influenza‐like syndromes. 2. 237 cases received the test drug and 241 were assigned to placebo. Patients recorded their rectal temperature twice a day, and the presence or absence of five cardinal symptoms (headache, stiffness, lumbar and articular pain, shivers) along with cough, coryza and fatigue. 3. Recovery was defined as a rectal temperature less than 37.5 degrees C and complete resolution of the five cardinal symptoms. 4. The proportion of cases who recovered within 48 h of treatment was greater among the active drug group than among the placebo group (17.1% against 10.3%, P = 0.03). 5. The result cannot be explained given our present state of knowledge, but it calls for further rigorously designed clinical studies.

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“…Since the 1970s, a large body of experimental work has been amassed, including work carried out in Russia [1][2][3][4][5][6][7], which shows that high dilutions no longer containing molecules of the original substance are able to cause a physiological reaction based on molecular-level effects. A number of properties commonly attributed to "high dilutions" have been discovered [8].…”

Section: Introductionmentioning

confidence: 99%

The Spatial Homeostasis Hypothesis

Epstein¹

2018

Symmetry

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From studies on the effects of "high dilutions" on organisms, it was found that their administration induces a delicate physiological (molecular and cellular) response. Occasionally, physiological reactions can become atypical (pathological) individual reactions. To resolve this paradox, the spatial homeostasis hypothesis has been proposed. It considers pathological processes as tools used by living systems, in order to retain their spatial integrity (symmetry), allowing them to properly reflect the geometry of the surrounding world and thus, to be a part of the evolutionary process. This article addresses an interdisciplinary subject and is aimed at natural scientists (physicists, chemists, and biologists) as well as philosophers.

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Effect on mouse peritoneal macrophages of orally administered very high dilutions of silica

Cited by 96 publications

References 16 publications

Quantum-like Interferences of Experimenter's Mental States: Application to “Paradoxical” Results in Physiology

Quantum-like Interferences of Experimenter's Mental States: Application to “Paradoxical” Results in Physiology

A controlled evaluation of a homoeopathic preparation in the treatment of influenza‐like syndromes.

The Spatial Homeostasis Hypothesis

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