Effect on hamster caries by purine derivatives vanillin and some tannin-containing materials caries in relation to food consumption and animal growth

Strålfors, A.

doi:10.1016/0003-9969(67)90215-4

Cited by 24 publications

(5 citation statements)

References 19 publications

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“…The sweetener products originated from the plant have no contra-indications and no side effects when related to its long term use (Stalfors 1967). Stevia is a non fermentable product that has low toxicity and high chemical stability when used in processed food (Aguiar 1986).…”

Section: Discussionmentioning

confidence: 99%

Stevia and sucrose effect on plaque formation

Slavutzky

2010

J. Verbr. Lebensm.

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An in vivo study was done by measuring the accumulation of dental plaque after rinsing with a solution of 10% sucrose four times daily during 5 days and comparing it with a rinsing of 10% solution of Stevia rebaudiana Bertoni four times a day, during 5 days a week. The accumulation of dental plaque after rinsing with Stevia was 57, 82% less than under rinsing with sucrose as measured by the Silness-Löe index and 10, 40% less plaque when measured by O'Leary index of plaque.

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Section: Discussionmentioning

confidence: 99%

Stevia and sucrose effect on plaque formation

Slavutzky

2010

J. Verbr. Lebensm.

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“…However, we have recently shown (Homer et al 1990) that aqueous extracts of plants used in Kenya as chewing sticks have marked effects on the degradation of model proteins and glycoproteins by putative periodontopathogens (Treponema denticola, Bacteroides intermedius and Porphyromonas {Bacteroides) gingivalis). The effects of plants extracts on bac-terial degradative activities have not previously been studied, but various plant extracts have been shown to inhibit, in vitro, the glucosyltransferase activity and growth of Streptococcus mutans and Streptococcus sobrinus (Wolinsky & Sote 1983, Kohda et al 1985, Southard et al 1984, Dzink & Socransky 1985, Wu-Yuan et al 1988, Gazi et al 1987, Stalfors 1967) and growth of Bacteroides spp. (Rotimi & Mosadomi 1983, Akpata & Akinrimisie 1977.…”

mentioning

confidence: 99%

“…The effects of plants extracts on bac-terial degradative activities have not previously been studied, but various plant extracts have been shown to inhibit, in vitro, the glucosyltransferase activity and growth of Streptococcus mutans and Streptococcus sobrinus (Wolinsky & Sote 1983, 1984, Kohda et al 1985, Southard et al 1984, Dzink & Socransky 1985, Wu-Yuan et al 1988, Gazi et al 1987, Stalfors 1967) and growth of Bacteroides spp. (Rotimi & Mosadomi 1983, Akpata & Akinrimisie 1977.…”

mentioning

confidence: 99%

Inhibition of peptidase and glycosidase activities of Porphyromonas gingivalis, Bacteroides intermedius and Treponema denticola by plant extracts

Homer

Manji

Beighton

1992

J Clinic Periodontology

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Aqueous extracts from 5 plants used widely in Kenya as chewing sticks (mswaki) for the control of oral hygiene were tested for their ability to inhibit extracellular peptidase and glycosidase enzyme activities produced by the periodontopathic bacteria Porphyromonas gingivalis (formerly Bacteroides gingivalis), Bacteroides intermedius and Treponema denticola. The plants studied were Rhus natalensis, Cupressus hisitanica, Sida cordifolia, Olea africana and Euclea divinorum. Protease activities, including glycylprolyl dipeptidase and trypsin-like activities of P. gingivalis, chymotrypsin-like and glycylprolyl dipeptidase activities of B. intermedius and the trypsin-like activity of T. denticola, were particularly affected by extracts from Rhus natalensis and Euclea divinorum. Glycosidase activities were generally less affected with the notable exceptions of the inhibition of beta-mannosidase activity of P. gingivalis by all extracts and the inhibition of neuraminidase activity of T. denticola by Rhus natalensis and Euclea divinorum. Generally, these same proteolytic and glycosidic activities were inhibited by tannic acid and to lesser extents by gallic acid and gallic acid methyl ester. An inhibitory component, present in all extracts, exhibited physical and chemical properties identical to those of tannic acid. The inhibition of these enzyme activities is likely to reduce the virulence of these periodontophathic bacteria and to reduce the rate of dental plaque formation.

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“…Great importance has been attached to tannic acid which also is a component of teas. Tannin reduces caries in animal experiments (8) and inhibits glycosyltransferase activity and adsorption of Streptococcus mutans to hydroxyapatite (9). Moreover, it has been shown that gallotannins inhibit growth and aggregation of Strep, mutans in vitro (10).…”

Section: Resultsmentioning

confidence: 99%

Plaque surface area after rinsing with a low‐level fluoride‐containing Darjeeling tea

Attin

Kilgers

Zimmermann

et al. 1995

European J Oral Sciences

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Plaque surface area after rinsing with a tea, containing low levels of fluoride, was evaluated in 30 human volunteers with a single-blind, one-operator, three-period, three-treatment cross-over study. The mouthwashes employed were: (1) tea (Darjeeling first flush:< 0.2 ppm F-), (2) Meridol(R), (3) control (tap water:< 0.2 ppm F-). During the experiment the participants refrained from oral hygiene procedures and rinsed their mouth three times a day after each meal with 20 ml of the respective rinse. After 3 d standardized photographs were taken of the upper canines and premolars and the plaque areas were measured planimetrically. Statistical analysis showed a marked decrease in plaque surface area after rinsing with Meridol, whereas no difference in plaque surface area was observed after mouthrinsing with tea and tap water, respectively.

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Effect on hamster caries by purine derivatives vanillin and some tannin-containing materials caries in relation to food consumption and animal growth

Cited by 24 publications

References 19 publications

Stevia and sucrose effect on plaque formation

Stevia and sucrose effect on plaque formation

Inhibition of peptidase and glycosidase activities of Porphyromonas gingivalis, Bacteroides intermedius and Treponema denticola by plant extracts

Plaque surface area after rinsing with a low‐level fluoride‐containing Darjeeling tea

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