Effect of β -lactamases associated to the resistance of β -lactam antibiotics on the treatment of wastewater

Rodríguez, Diana Catalina; Ahammad, Ziauddin S.; Peñuela, Gustavo A.; Graham, David W.

doi:10.1016/j.jece.2018.03.006

Cited by 2 publications

(1 citation statement)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to the characteristic enzymes produced by the target of bacterial infection, bacteria themselves have characteristic endogenous enzymes [ 88 ]. For example, NTR, a flavin-containing enzyme, mainly exists in bacteria, archaea, and eukaryotes; alkaline phosphatase, which is highly expressed by bacteria, is mainly located in the periplasmic region of the bacterial surface wall and is associated with the outer membrane; β -lactamase, a hydrolytic enzyme, is the main means of resistance to β -lactamase antibiotics by drug-resistant bacteria [ 89 , 90 , 91 ]. Therefore, it is possible to target NTR, alkaline phosphatase, and β -lactamase for fluorescence imaging of specific bacteria.…”

Section: Identification Of Endogenous Enzymes Of Pathogenic Bacteriamentioning

confidence: 99%

Recent Progress in Identifying Bacteria with Fluorescent Probes

Wang

et al. 2022

Molecules

View full text Add to dashboard Cite

The development of new techniques to rapidly and accurately detect bacteria has drawn continuous attention due to the potential threats posed by bacteria to human health and safety. Recently, a novel strategy based on fluorescent probes has drawn considerable interest for the detection of bacteria due to its high selectivity, fast response, and simple operation. In this review, we summarize the recent progress on fluorescent probes for the specific recognition and discrimination of Gram-negative and Gram-positive bacteria. In particular, we outline current design strategies, such as targeting of the differences in surface components, cell wall components, endogenous enzymes, surface charge, and hydrophobicity of various kinds of bacteria to develop various fluorescent sensors (organic small-molecule fluorescent probes, nanoprobes, and metal ion probes). We also emphasize the application of organic molecules in probe recognition elements. We hope that this review can stimulate this research area in bacterial detection and imaging in the future.

show abstract