Effect of zinc supplementation on blood sugar control in the overweight and obese population: A systematic review and meta-analysis of randomized controlled trials

Yang, Hao-Yu; Hung, King-Chü; Chuang, Min‐Hsiang; Chang, Renin; Chen, Ru-Yih; Wang, Fuwei; Wu, Jheng‐Yan; Chen, Jui-Yi

doi:10.1016/j.orcp.2023.06.003

Cited by 5 publications

(1 citation statement)

References 47 publications

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“…The effects of some of the micronutrients on glucose homeostasis were dosedependent. The doses recommended in meta-analyses to achieve optimal effects were ≥4000 IU/day for vitamin D [89], between 400 and 700 mg/day for vitamin E [57], ≥1000 mg/day for vitamin C [115], ≥5 mg/day for vitamin B9 [116], 200 µg/day for Se [118], and ≥30 mg for Zn [119].…”

Section: Effects Of Micronutrient Supplementation On Glucose Homeostasismentioning

confidence: 99%

The Importance of Micronutrient Adequacy in Obesity and the Potential of Microbiota Interventions to Support It

Rudzka,

Kapusniak,

Zielińska

et al. 2024

Applied Sciences

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Micronutrient deficiencies co-occur with obesity throughout the world. While many factors may contribute to this, microbiota dysbiosis is certainly one that has received a lot of attention in recent years. This work aimed to review the current state of knowledge on the role of micronutrients in obesity and the effects of interventions in microbiota on the micronutrient status of humans. Gathered evidence suggested that the supplementation of most of the deficient micronutrients for people with excess weight may have a considerable, positive impact on lipid and glucose homeostasis and a small effect on weight loss. Interestingly, the doses of micronutrient supplementation that allowed for achieving the best results for most of the minerals and vitamins exceeded the tolerable upper intake levels. To avoid negative effects associated with an overdose of vitamins and minerals, applying microbiota interventions could be considered. Pro- and prebiotics were shown to improve the micronutrient status of humans, and several publications indicated that when applied together with vitamins and minerals, they could give greater benefits than each of these treatments alone. Therefore, supplementation with vitamins, minerals, and pro/pre/synbiotics in obesity treatment plans may be recommended; however, further research is required to mitigate risks and optimize the effects achieved.

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Section: Effects Of Micronutrient Supplementation On Glucose Homeostasismentioning

confidence: 99%

The Importance of Micronutrient Adequacy in Obesity and the Potential of Microbiota Interventions to Support It

Rudzka,

Kapusniak,

Zielińska

et al. 2024

Applied Sciences

View full text Add to dashboard Cite

show abstract

“Green” synthesized versus chemically synthesized zinc oxide nanoparticles: In vivo antihyperglycemic activity and pharmacokinetics

Kambale,

Domingues,

Zhang

et al. 2024

International Journal of Pharmaceutics

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Letter to the Editor: Comment on “Effect of zinc supplementation on blood sugar control in the overweight and obese population: A systematic review and meta-analysis of randomized controlled trials”

Zanella

2024

Obesity Research & Clinical Practice

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Effect of zinc supplementation on blood sugar control in the overweight and obese population: A systematic review and meta-analysis of randomized controlled trials

Cited by 5 publications

References 47 publications

The Importance of Micronutrient Adequacy in Obesity and the Potential of Microbiota Interventions to Support It

The Importance of Micronutrient Adequacy in Obesity and the Potential of Microbiota Interventions to Support It

“Green” synthesized versus chemically synthesized zinc oxide nanoparticles: In vivo antihyperglycemic activity and pharmacokinetics

Letter to the Editor: Comment on “Effect of zinc supplementation on blood sugar control in the overweight and obese population: A systematic review and meta-analysis of randomized controlled trials”

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