Effect of Zearalanol on the Performance and Carcass Composition of Growing-Finishing Ruminants

Sharp, Gillian; Dyer, I. A.

doi:10.2527/jas1971.334865x

Cited by 48 publications

(22 citation statements)

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“…However, higher scores (P<.05) for both skeletal maturity and final maturity indicated that I bull carcasses were more mature physiologically than NI bull carcasses, even though the I animals were slaughtered at younger chronological ages. Our results are in contrast with the findings of Sharp and Dyer (1971), who suggested that Ralgro delayed physiological maturity of growing steers, heifers and wether lambs.…”

Section: Carcass Characteristics Hot Carcass Weightscontrasting

confidence: 56%

Ralgro-Implanted Bulls: Performance, Carcass Characteristics, Longissimus Palatability and Carcass Electrical Stimulation

Greathouse

Hunt

Dikeman

et al. 1983

Journal of Animal Science

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Section: Carcass Characteristics Hot Carcass Weightscontrasting

confidence: 56%

Ralgro-Implanted Bulls: Performance, Carcass Characteristics, Longissimus Palatability and Carcass Electrical Stimulation

Greathouse

Hunt

Dikeman

et al. 1983

Journal of Animal Science

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“…Les jeunes bouvillons portant un implant de z6ranol avaient respectivementpr\s 4,2 et 5,0% de plus (P<0,01) que les t6moins lors des essais de 1980 (0,98 contre 0,94 kg/jour) et de 1981 (1,06 contre I,01 kg/j). Les jeunes g6nisses trait6es de la m€me fagon avaient grossi 3,57o (P<0,05) et 7,4Vo 120 The effectiveness of zeranol [6-(6,10-dihydroxyundecyl)-B-resorcylic acid-ulactone] and progesterone-estradiol as growth stimulants for feedlot cattle has been amply demonstrated (Perry et al 1970; Sharp and Dyer 1971; Gates 1976; Kahl et al 1978 Embry et al 1981). However, only limited information is available on the effect of zeranol on growth in suckling calves (Lewis et al 1979; Lamm et al 1980) (Harvey 1960 (Steel and n -"i9 4n"9 "qqc cq q q q qq qqq \09q q09 q -oooo-ooo*-oooo-<oo-ooo-oo o -q \ q v?…”

mentioning

confidence: 99%

Growth Response of Beef Cattle at Pasture to Zeranol or Progesterone-Estradiol Implants

Basarab¹,

Gould²,

Weisenburger³

1984

Can. J. Anim. Sci.

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“…1999). Moreover, Sharp and Dyer (1971) reported that treatment of lambs with zeranol increased muscle mass via protein synthesis. In the present study, the striated muscles had higher AgNOR counts and a lower PCNA index than other cellular components in treatment groups.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Proliferative Activity by AgNOR and PCNA in Prostatic Tissues of Ram Lambs Implanted with Zeranol

Gulbahar

Yüksel

Güvenç

et al. 2005

Reprod Domestic Animals

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The aim of this study was to assess cellular proliferation using silver-stained nucleolar organizer regions (AgNOR) and the proliferating cell nuclear antigen (PCNA) in various tissues in the prostate of ram lambs implanted with increasing zeranol doses and to compare the sensitivity of different tissues of lamb prostate to zeranol. Twenty-four Akkaraman lambs were implanted with increasing zeranol doses, including 12 mg (n = 8), 24 mg (n = 8) and 96 mg (n = 8), with eight lambs serving as controls. After 33 days, the prostate tissues of the lambs were stained using AgNOR and PCNA techniques. The prostate tissues were divided into two compartments--the epithelial tissues, including glandular acinus, collecting duct and penile urethra, and the non-epithelial tissues, including interstitial tissue and striated muscle. AgNOR dots and PCNA index on each prostatic tissue were counted under a light microscope and were evaluated statistically. AgNOR staining in the treatment groups showed a higher score in the non-epithelial tissues than the epithelial components, whereas the PCNA index was significant in the epithelial tissues and non-epithelial tissues had very low PCNA immunostaining. According to the PCNA index, collecting duct epithelium showed more sensitivity to increasing zeranol doses and according to AgNOR counts, there was no difference of sensitivity to zeranol among tissues of the same origin. Both AgNOR counts and PCNA indexes seem to be valuable proliferating markers for the epithelial components of ram prostate, but PCNA index had no significance in relation to the non-epithelial components in contrast to AgNOR counts. Therefore, the controversial results arising from the combined use of both techniques as proliferating markers for the ram prostate should be considered in further studies.

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Effect of Zearalanol on the Performance and Carcass Composition of Growing-Finishing Ruminants

Cited by 48 publications

References 0 publications

Ralgro-Implanted Bulls: Performance, Carcass Characteristics, Longissimus Palatability and Carcass Electrical Stimulation

Ralgro-Implanted Bulls: Performance, Carcass Characteristics, Longissimus Palatability and Carcass Electrical Stimulation

Growth Response of Beef Cattle at Pasture to Zeranol or Progesterone-Estradiol Implants

Assessment of Proliferative Activity by AgNOR and PCNA in Prostatic Tissues of Ram Lambs Implanted with Zeranol

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