Effect of ytterbium amount on LaNbO4:Tm3+,Yb3+ nanoparticles for bio-labelling applications

Marques, Nathalia da Silva; Nassar, Eduardo J.; Verelst, Marc; Mauricot, Robert; Bruncková, Helena; Rocha, Lucas A.

doi:10.1016/j.advms.2020.06.001

Cited by 8 publications

(4 citation statements)

References 46 publications

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“…They have focused on using calcium fluoride co-doped with rare-earth ions such as ytterbium, gadolinium, and neodymium (CaF 2 : Yb, Gd, Nd) NPs. It has conclusively been shown that [129] Yb 3+ concentration in LaNbO 4 nanoparticles affects the luminescent properties of NPs for medical imaging applications, and the intensity of emissions is directly related to Yb 3+ concentration. Recently, an in-vivo study has shown that BaYbF 5 -SiO 2 NPs can be used as contrast agents for imaging the osteochondral interface with micro-CT imaging with high-resolution images [130].…”

Section: Ytterbium-based Nanoparticlesmentioning

confidence: 99%

Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review

2023

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In recent years, there has been an increasing interest in using nanoparticles in the medical sciences. Today, metal nanoparticles have many applications in medicine for tumor visualization, drug delivery, and early diagnosis, with different modalities such as X-ray imaging, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), etc., and treatment with radiation. This paper reviews recent findings of recent metal nanotheranostics in medical imaging and therapy. The study offers some critical insights into using different types of metal nanoparticles in medicine for cancer detection and treatment purposes. The data of this review study were gathered from multiple scientific citation websites such as Google Scholar, PubMed, Scopus, and Web of Science up through the end of January 2023. In the literature, many metal nanoparticles are used for medical applications. However, due to their high abundance, low price, and high performance for visualization and treatment, nanoparticles such as gold, bismuth, tungsten, tantalum, ytterbium, gadolinium, silver, iron, platinum, and lead have been investigated in this review study. This paper has highlighted the importance of gold, gadolinium, and iron-based metal nanoparticles in different forms for tumor visualization and treatment in medical applications due to their ease of functionalization, low toxicity, and superior biocompatibility.

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Section: Ytterbium-based Nanoparticlesmentioning

confidence: 99%

Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review

2023

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“…Various studies have demonstrated that the concentration of Yb 3+ in LaNbO 4 nanoparticles greatly affects the luminescent property for medical imaging application. The concentration of Yb 3+ greatly affects the intensity of emission . A recent in vivo investigation has revealed the potential utility of BaYbF 5 –SiO 2 nanoparticles as contrasting agents for imaging the osteochondral interface through high-resolution micro-CT imaging .…”

Section: Nanoparticles Used For Theranostic Purposesmentioning

confidence: 99%

“…The concentration of Yb 3+ greatly affects the intensity of emission. 167 A recent in vivo investigation has revealed the potential utility of BaYbF 5 −SiO 2 nanoparticles as contrasting agents for imaging the osteochondral interface through highresolution micro-CT imaging. 168 Yuan et al 169 synthesized nanocomposites fabricated from NaYF 4 :Yb/Er along with UiO-66-NH 2 used for luminescence-monitored drug delivery, anticounterfeiting, and photodynamic therapy (Figure 3).…”

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confidence: 99%

Nanomaterials as Theranostic Agents for Cancer Therapy

Bauri,

Tripathi,

Choudhury

et al. 2023

ACS Appl. Nano Mater.

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“…The intriguing aspect of the upconversion nanoparticles is that the particles can be excited with humanly invisible nearinfrared radiation, which is available in nature with other radiation and can result in anti-stoke radiation in the visible wavelength range with a longer lifetime due to sequential absorption of photons [25]. The advantage of NIR excitation with an absence of autofluorescence in biological specimens makes them as the preferred candidate for tissue imaging and bio-labelling [26,27].…”

Section: Introductionmentioning

confidence: 99%

Microwave-assisted synthesis and upconversion luminescence of NaYF4:Yb, Gd, Er and NaYF4:Yb, Gd, Tm nanorods

Nannuri¹,

Singh²,

Misra³

et al. 2022

Methods Appl. Fluoresc.

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Anisotropic rare-earth ion (RE3+) doped fluoride upconversion particles are emerging as a potential candidate in diverse areas, ranging from biomedical imaging to photonics. Here, we develop a facile strategy to synthesize NaYF4:Yb, Er, Gd and NaYF4:Yb, Tm, Gd upconversion nanorods via microwave synthesis route by controlling the synthesis time and compared the optical properties of similar nanorods prepared via solvothermal technique. With the increase in synthesis time, the phase of the particle was found to change from mixed-phase to purely hexagonal and the morphology of the particles change the mixed phase of spherical and rod-shaped particles to completely nanorods for a synthesis time of 60 minutes. Further, the intrinsically hydrophobic particles changed to hydrophilic by removal of oleic capping via acid treatment and the amine-functionalized silica coating. The upconversion luminescence, as well as laser power-dependent emission properties of the surface-modified particles, elucidate that the surface modification route influence the upconversion luminescence as well as solvent-dependent emission properties. Moreover, the laser power-dependent studies elucidate that the upconversion process in a multi-photon process.

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Effect of ytterbium amount on LaNbO4:Tm3+,Yb3+ nanoparticles for bio-labelling applications

Cited by 8 publications

References 46 publications

Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review

Recent Metal Nanotheranostics for Cancer Diagnosis and Therapy: A Review

Nanomaterials as Theranostic Agents for Cancer Therapy

Microwave-assisted synthesis and upconversion luminescence of NaYF4:Yb, Gd, Er and NaYF4:Yb, Gd, Tm nanorods

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