Effect of Yacon &lt;i&gt;(Smallanthus sonchifolius)&lt;/i&gt; on Colonic Transit Time in Healthy Volunteers

Geyer, M.; Manrique, Ivan; Degen, Lukas; Beglinger, Christoph

doi:10.1159/000155214

Cited by 53 publications

(38 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Delgado et al 31 reviewed the potential of yacon, a tuberous Andean plant that presents high content of fructooligosaccharides and inulin [32][33] Merino-Aguilar et al 35 treated obese rats with FOS fraction extracted from Psacalium decompositum for 12 weeks and found decreased body weight, cholesterol, triglycerides, and significantly reduced cytokines IL-6, IFN-γ, MCP-1, IL-1β and VEGF levels (p<0.05) 35 .…”

Section: Fos Effects On Plasma Cholesterolmentioning

confidence: 99%

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

Costa

Abreu²,

Guimarães³

et al. 2015

Acta Cir. Bras.

View full text Add to dashboard Cite

PURPOSE:To address the effects of fructooligosaccharides (FOS) intake on serum cholesterol levels. METHODS:We performed a search for scientific articles in MEDLINE database from 1987 to 2014, using the following English keywords: fructooligosaccharides; fructooligosaccharides and cholesterol. A total of 493 articles were found. After careful selection and exclusion of duplicate articles 34 references were selected. Revised texts were divided into two topics: "FOS Metabolism" and "FOS effects on plasma cholesterol." RESULTS:The use of a FOS diet prevented some lipid disorders and lowered fatty acid synthase activity in the liver in insulin-resistant rats. There was also reduction in weight and total cholesterol in beagle dogs on a calorie-restricted diet enriched with short-chain FOS. Another study found that 2g FOS daily consumption increased significantly serum HDL cholesterol levels but did not ensure a significant reduction in levels of total cholesterol and triglycerides.. Patients with mild hypercholesterolemia receiving short-chain FOS 10.6g daily presented no statistically significant reduction in serum cholesterol levels. However, when FOS was offered to patients that changed their lifestyle, the reduction of LDL cholesterol and steatosis was higher. CONCLUSIONS:Fructooligosaccharides intake may have a beneficial effect on lipid metabolism and regulation of serum cholesterol levels in individuals that change their lifestyle. FOS supplementation use in diets may therefore be a strategy for lowering cholesterol.

show abstract

Section: Fos Effects On Plasma Cholesterolmentioning

confidence: 99%

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

Costa

Abreu²,

Guimarães³

et al. 2015

Acta Cir. Bras.

View full text Add to dashboard Cite

show abstract

“…Su consumo reconstituye la microflora benéfica del colon, reduce el colesterol sanguíneo, mejora la asimilación de calcio, corrige el estreñimiento y PRODUCCIÓN DE SEMILLA SEXUAL EN YACÓN Julio -Diciembre 2014 __________________________________________________________________________________________ 136 fortalece el sistema inmunológico (Geyer et al, 2008;Genta et al, 2009). El yacón además es un alimento ideal para diabéticos y para personas que desean bajar de peso ya que su consumo no eleva la concentración de glucosa en la sangre y aporta muy pocas calorías a la dieta.…”

Section: Introductionunclassified

PRODUCCIÓN DE SEMILLAS EN YACÓN (Smallanthus sonchifolius (Poepp. & Endl.)) MEDIANTE TÉCNICAS DE POLINIZACIÓN CONTROLADAS

et al. 2014

View full text Add to dashboard Cite

ResumenEl yacón, una raíz de origen andino, es una fuente abundante de fructooligosacáridos (FOS) y compuestos fenólicos. Su consumo ha sido asociado con la prevención de enfermedades crónicas (dislipidemias y resistencia a la insulina), cáncer de colon, estreñimiento, entre otras propiedades. La propagación del yacón es eminentemente clonal. Se han sugerido mecanismos de androesterilidad y una escasa o nula viabilidad en las semillas, lo que imposibilitarían su reproducción sexual en condiciones naturales y controladas. En el presente trabajo se realizaron cruzamientos entre seis accesiones de yacón (cuatro octoploides y dos dodecaploides) con la finalidad de obtener híbridos F1 y generar información acerca de la producción y viabilidad de las semillas. Para ello, se usó un diseño de cruzas dialélicas, directas y recíprocas, de las que se generaron 30 cruzas F1. En total se polinizaron 1 746 inflorescencias y se obtuvieron 1 181 semillas llenas. En todos los cruzamientos planificados se produjo semilla, excepto en aquellos cruzamientos en los que los progenitores dodecaploides actuaron como femeninos. Cuando las semillas llenas fueron escarificadas y sembradas en sustrato orgánico se logró obtener un porcentaje de germinación de 38.4%. En promedio se necesitaron polinizar cuatro inflorescencias de yacón por cada semilla viable que se obtuvo. La factibilidad de producir semillas de yacón empleando polinizaciones controladas abre oportunidades para plantear investigaciones en la biología reproductiva del cultivo, probar la teoría del origen alopoliploide del yacón, obtener variedades mejoradas y estudiar nuevas estrategias de conservación y distribución de germoplasma de yacón. Palabras clave: Híbrido, yacón, semilla, polinización, octoploide, dodecaploide Abstract Yacon, an Andean root crop, is a plentiful source of fructooligosaccharides (FOS) and phenolic compounds. Its consumption has been related to the prevention of chronic diseases (dyslipidemia and insulin resistance), colon cancer, constipation, among other properties. Yacon reproduction is eminently clonal. Mechanisms of male sterility and scarce or null viability in the seeds have been suggested in yacon, which would preclude its sexual reproduction in natural or controlled conditions. In this work, six yacon accessions (four octoploids and two dodecaploids) were cross-pollinated in order to obtain F1 hybrids and generate information about the production and viability of the seeds. A dialelic design was used, with direct and reciprocal crosses, which generated 30 F1 crosses. A total of 1 746 inflorescences were pollinated and 1 181 seeds were obtained. All crosses produced seeds, except those crosses where dodecaploid progenitors worked as female. A high value of germination (38.39%) was obtained when the seeds were scarified and planted in an organic substrate (moss and peat moss). On average it was necessary to pollinate four inflorescences to obtain one viable yacon seed. The feasibility to produce yacon seeds opens opportunities to propose studies ...

show abstract

“…The dose of the hydroalcoholic extracts of the leaves was 400 mg per Kg body weight as in a previous study [12]. The dose of the root extract was 1.06 mg per Kg, corresponding to 340 mg fructooligosaccharides per Kg, a value also based on previous investigations [9] [20] [29].…”

Section: Experimental Designmentioning

confidence: 97%

The in Vitro Antioxidant Capacities of Hydroalcoholic Extracts from Roots and Leaves of Smallanthus sonchifolius (Yacon) Do Not Correlate with Their in Vivo Antioxidant Action in Diabetic Rats

Biazon¹,

Wendt²,

Moreira³

et al. 2016

JBM

View full text Add to dashboard Cite

Leaf and root extracts of Smallanthus sonchifolius (yacon), have antihyper-glycemic activity and antioxidant properties. The present study aims to compare the in vivo hepatic antioxidant activity of hydroalcoholic extracts of yacon leaves and roots in rats with streptozotocin-induced diabetes in terms of their in vitro antioxidant capacity. Rats were treated during 14 days with 1060 mg•Kg −1 root extract or 400 mg•Kg −1 leaf extract. The latter was richer in phenolics and possessed a much higher in vitro antioxidant activity. Both extracts prevented hyperglycemia in diabetic rats. The liver of diabetic rats presented increased levels of protein carbonyls and ROS and decreased activities of antioxidant enzymes. Treatment with both root and leaf extracts restored the protein carbonyl levels to normality. The root extract also restored the ROS levels to normality, but the leaf extract was not effective. The root extract was also more effective in restoring the activity of at least two important antioxidant enzymes (glucose 6-phosphate dehydrogenase and glutathione peroxidase). In terms of the antioxidant load (which was 17 times lower in the root extract treatment), the in vivo action of the root extract was more effective than the leaf extract in reducing the hepatic oxidative stress that accompanies diabetes.

show abstract

Effect of Yacon <i>(Smallanthus sonchifolius)</i> on Colonic Transit Time in Healthy Volunteers

Cited by 53 publications

References 20 publications

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

PRODUCCIÓN DE SEMILLAS EN YACÓN (Smallanthus sonchifolius (Poepp. & Endl.)) MEDIANTE TÉCNICAS DE POLINIZACIÓN CONTROLADAS

The <i>in Vitro</i> Antioxidant Capacities of Hydroalcoholic Extracts from Roots and Leaves of <i>Smallanthus sonchifolius</i> (Yacon) Do Not Correlate with Their <i>in Vivo</i> Antioxidant Action in Diabetic Rats

Contact Info

Product

Resources

About

Effect of Yacon <i>(Smallanthus sonchifolius)</i> on Colonic Transit Time in Healthy Volunteers

Cited by 53 publications

References 20 publications

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

Fructo-oligosaccharide effects on serum cholesterol levels. An overview

PRODUCCIÓN DE SEMILLAS EN YACÓN (Smallanthus sonchifolius (Poepp. & Endl.)) MEDIANTE TÉCNICAS DE POLINIZACIÓN CONTROLADAS

The &lt;i&gt;in Vitro&lt;/i&gt; Antioxidant Capacities of Hydroalcoholic Extracts from Roots and Leaves of &lt;i&gt;Smallanthus sonchifolius&lt;/i&gt; (Yacon) Do Not Correlate with Their &lt;i&gt;in Vivo&lt;/i&gt; Antioxidant Action in Diabetic Rats

Contact Info

Product

Resources

About

The <i>in Vitro</i> Antioxidant Capacities of Hydroalcoholic Extracts from Roots and Leaves of <i>Smallanthus sonchifolius</i> (Yacon) Do Not Correlate with Their <i>in Vivo</i> Antioxidant Action in Diabetic Rats