Effect of Y-20811, a thromboxane synthetase inhibitor, on photochemically induced cerebral embolism in rabbits

Y‐20811: A Long‐acting Thromboxane A2 Synthase Inhibitor

“…The embolism from carotid artery is thought to be the major cause of TIAs (47). Fujimura et al developed a new model of embolic cerebral infarction induced in rabbits by photochemical injury of internal lumen of common carotid artery (14). Seven days after the injury, cerebral infarcts, ranging from 0.2-1 mm in size, appeared on the surface of cortex and platelet emboli were observed with light microscope in carotid artery as well as in cortical arterioles.…”