“…Lately, research has highlighted the implications of the gut microbiota on human health, with SCFAs being correlated with reducing luminal pH and having protective action against acid-sensitive enteropathogens [ 24 , 25 , 26 , 27 , 28 ]. In recent years, XOS have been incorporated in various food applications (cookies, dairy products, beverages, fruit juices and chewing gums) [ 29 , 30 , 31 , 32 ], animal feed [ 33 ] and nutraceuticals [ 16 , 34 ], showing better physicochemical properties such as thermal stability (up to 100 °C) and acidity (pH 2.5 to 8) compared to the well-known inulin and fructooligosaccharides [ 5 , 12 , 35 ]. In Japan, XOS are approved as food ingredients by the Japanese Ministry of Health, Labour and Welfare, as Foods for Specified Health Uses (FOSHU), while in China they have been on the market since 2000 as food supplements [ 36 ].…”