Effect of xylazine administration before laparoscopic abomasopexy to correct left displaced abomasum on markers of stress in dairy cows

Abstract

Left displacement of the abomasum in dairy cows is a disease diagnosed all over the world. In Germany, a common method for its correction is laparoscopic abomasopexy (LA). The aim of the study was to assess cortisol and substance P concentrations, behavioral patterns, and feeding and rumination times during and after LA in cattle treated with xylazine before LA compared with nonsedated cattle. A total of 28 cattle that had been referred to a veterinary teaching hospital with a diagnosis of left displacement of the abomasum were randomly assigned to 1 of 2 groups. Surgery was performed according to a standardized protocol. Animals of XYL (n = 14) received xylazine (0.02 mg/kg body weight i.v.) before surgery, and animals of CON (n = 14) received a placebo (0.9% saline i.v.). All cows received ketoprofen (3 mg/kg body weight i.v.) twice, and benzyl penicillin procaine (20,000 IU/kg body weight i.m.) for 5 ± 1 d.

The effect of flunixin meglumine on eating and rumination variables in cows after omentopexy for correction of left displaced abomasum

“…7 Likewise, cows with LDA that had received xylazine before omentopexy had significantly greater numbers of chewing cycles per regurgitated bolus than non-treated cows (55.5 vs 46.6). 12 These findings support the recommendation of others 172 min (Group 2B) and 216 min (Group 2C) (P < 0.01) and was in the reference interval from day 2 onward. It increased further by day 30 reaching values of 305, 310 and 313 min, respectively.…”

Methods for Pain Assessment in Calves and Their Use for the Evaluation of Pain during Different Procedures—A Review

“…Facial expressions were significantly different between cows not in pain compared with animals in pain [ 6 ]. Features of the pain face have been used for pain assessment in adult cattle following different procedures [ 8 , 51 , 53 ]. In calves, the use of the characteristics of the pain face or pain ears has been first described in 2017 [ 54 ].…”

The Effect of Stress on Reproduction and Reproductive Technologies in Beef Cattle—A Review

“…Serum amyloid-A proteins, which are apolipoproteins associated with the high-density lipoprotein, are synthesized by the liver during the acute-phase response [52]. Although originally used as a pain biomarker [87][88][89][90], substance P can be used as a stress biomarker. Kasimanickam's group, for example, showed that its levels were higher in aggressive dairy heifers than in mild or calm heifers [91] and that its levels increased in beef heifers after undergoing Artificial Insemination at fixed time (FTAI) [92].…”

“…Kasimanickam's group, for example, showed that its levels were higher in aggressive dairy heifers than in mild or calm heifers [91] and that its levels increased in beef heifers after undergoing Artificial Insemination at fixed time (FTAI) [92]. Substance P can be assayed in blood using enzyme-linked immunoassays or enzyme-linked immunosorbent assays and samples can first be frozen [87,90,92]. Prolactin was originally considered a potential stress biomarker because its levels in beef heifers depend on their temperament [92] but it is not routinely used in this way because its levels are strongly influenced by dairy husbandry practices, as well as by light levels and temperature [93].…”