Effect of Westphal Lipid A on Viral Activities in Mice and Hamsters

Nemes, Marjorie M.; Hilleman, Maurice R.

doi:10.3181/00379727-110-27563

Search citation statements

Order By: Relevance

Paper Sections

Select...

It Is Seen In2

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1963

1977

Publication Types

Select...

Article5

Other1

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 6 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mechanism of action of the lipid A and endotoxin in inducing resistance to viruses is unknown, but Nemes and Hilleman (1962) suggest that enhanced functional capacity of the reticuloendothelial system is a factor. This is supported by the work of Biozzi et al (1955).…”

Section: It Is Seen Inmentioning

confidence: 99%

See 1 more Smart Citation

The Effect of Zymosan and Endotoxin Treatment on Experimental Coxsackie B Virus Infection

Marcus¹,

Miya²,

Phelps³

1963

View full text Add to dashboard Cite

show abstract

Section: It Is Seen Inmentioning

confidence: 99%

“…Recently Nemes and Hilleman (1962) reported that Westphal's lipid A, which has endotoxic activity, enhanced nonspecific host resistance to the neurotoxicity of neurotropic influenza and herpes simplex viruses. In addi-.…”

Section: It Is Seen Inmentioning

confidence: 99%

The Effect of Zymosan and Endotoxin Treatment on Experimental Coxsackie B Virus Infection

Marcus¹,

Miya²,

Phelps³

1963

View full text Add to dashboard Cite

show abstract

Interferon in prospect and perspective

Hilleman

1963

J. Cell. Comp. Physiol.

View full text Add to dashboard Cite

Effect of pretreatment with immune serum on murine sarcoma virus (Moloney) tumour induction and growth

Guiliani¹,

Casazza²,

Soranzo³

et al. 1977

Br J Cancer

View full text Add to dashboard Cite

Summary.-Regressor serum from MSV-M-infected mice markedly reduced MSV-M oncogenesis when administered i.p. (0-1 ml/mouse) as much as 30 days before i.m. MSV-M infection in adult BALB/c mice. The regressor serum activity appeared to be directly dependent on the amount of IgG, as shown by: (1) inactivity of sera which have low virus-neutralizing antibody content; (2) high effectiveness only of the IgG serum fraction; (3) inactivity of regressor serum incubated with anti-mouse gamma-globulin serum. The regressor serum activity was specific and could not be ascribed to interferon or interferon-inducing factors, antigenantibody complexes or free antigen. The activity was not suppressed by sublethal irradiation (380 rad) of recipient mice. These results suggest that the activity of regressor serum administered before MSV-M infection is mediated through sensitization of host cells which are not radiosensitive.

show abstract

Effect of Westphal Lipid A on Viral Activities in Mice and Hamsters

Cited by 6 publications

References 1 publication

The Effect of Zymosan and Endotoxin Treatment on Experimental Coxsackie B Virus Infection

The Effect of Zymosan and Endotoxin Treatment on Experimental Coxsackie B Virus Infection

Interferon in prospect and perspective

Effect of pretreatment with immune serum on murine sarcoma virus (Moloney) tumour induction and growth

Contact Info

Product

Resources

About