Effect of weight loss on cardiac chamber size, wall thickness and left ventricular function in morbid obesity

Alpert, Martin A.; Terry, Boyd E.; Kelly, Diana L.

doi:10.1016/0002-9149(85)90156-0

Cited by 187 publications

(96 citation statements)

References 20 publications

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“…17,18 Although few specific references to bariatric candidates could be identified in the literature, it is reasonable to propose that more encouraging outcomes would be elicited if progressive physical conditioning were offered to this population jointly with surgical therapy. [26][27][28][29][30] …”

Section: Discussionmentioning

confidence: 99%

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

et al. 2004

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PURPOSE:Aerobic capacity and respiratory function may be compromised in obesity, but few studies have been done in highly obese bariatric candidates. In a prospective study, these variables were documented in the preoperative period, aiming to define possible physiologic limitations in a apparently healthy and asymptomatic population.METHOD: Forty-six consecutively enrolled adults (age 39.6 ± 8.4 years, 87.0% females, body mass index /BMI 49.6 ± 6.3 kg/m 2 ) were analyzed. Ventilatory variables were investigated by automated spirometry, aerobic capacity was estimated by a modified Bruce test in an ergometric treadmill, and body composition was determined by bioimpedance analysis.RESULTS: Total fat was greatly increased (46.4 ± 4.6% of body weight) and body water reduced (47.3 ± 4.6 % body weight), as expected for such obese group. Spirometric findings including forced vital capacity of 3.3 ± 0.8 L and forced expiratory volume-1 second of 2.6 ± 0.6 L were usually acceptable for age and gender, but mild restrictive pulmonary insufficiency was diagnosed in 20.9%. Aerobic capacity was more markedly diminished, as reflected by very modest maximal time (4.5 ± 1.1 min) and distance (322 ±142 m) along with proportionally elevated maximal oxygen consumption (23.4 ± 9.5 mL/kg/min) achieved by these subjects during test exercise.CONCLUSIONS: 1) Cardiopulmonary evaluation was feasible and well-tolerated in this severely obese population; 2) Mean spirometric variables were not diminished in this study, but part of the population displayed mild restrictive changes; 3) Exercise tolerance was very negatively influenced by obesity, resulting in reduced endurance and excessive metabolic cost for the treadmill run; 4) More attention to fitness and aerobic capacity is recommended for seriously obese bariatric candidates;

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Section: Discussionmentioning

confidence: 99%

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

et al. 2004

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“…Class III obesity is associated with increased left ventricular mass, with lower systolic function and significant worsening of the left ventricular diastolic function. Dilated cardiomyopathy is the leading cause of sudden death in the morbidly obese (caused mainly by arrhythmias), characterized by cardiomegaly, left ventricular dilatation and hypertrophy of cardiac muscle fibers 3 .…”

Section: Discussionmentioning

confidence: 99%

Emagrecimento e desempenho cardíaco

Valezi¹,

Machado²

2011

ABCD, arq. bras. cir. dig.

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-Background -Cardiovascular diseases are the most frequent complications associated with obesity. The weight loss determine blood pressure decrease and improvement in parameters of lipid and glucose levels. Weight loss and maintenance reduce the risk factors for cardiovascular disease, making reversible cardiac changes resulting from obesity. Aim -To evaluate the effect of weight loss on physical capacity and the structural and functional heart of obese patients undergoing to bariatric surgery. Methods -Forty-three patients who underwent gastric Roux-en-Y bypass, were analyzed by ECG, and echocardiography preoperatively and one year after the bypass. Statistical analysis used the Wilcoxon and Student t test, Shapiro-Wilk test with a significance level of 5%. Results -The weight decreased from 116.5 kg to 21.5 ± 15.9 ± 80 kg, BMI of 41.8 kg/m 2 ± 4.4 to 28.4 kg/m 2 ± 3.8, heart rate decreased from 77.9 ± 9.6 bpm to 70.9 ± 7.8 bpm, systolic pressure of 130 ± 20 mmHg to 120 mmHg ± 10, diastolic 80 mmHg ± 10 mmHg to 80 ± 0. The exercise test showed increases in distance traveled of 378.9 m ± 126.5 m to 140.4 ± 595m; coefficient in metabolic equivalents (METs) from 6.7 ± 2.4 ml O 2 / kg / min to 8.3 ± 2.6 ml O 2 / kg / min, oxygen consumption (VO 2) 23.1 ± 8.4 to 10.3 ± 30. The echocardiogram showed a reduction in the interventricular septum of 12 mm to 10 mm ± 2 ± 1; posterior wall of 11 mm to 10 mm ± 2 ± 1; ventricular mass of 273 ± 85 g to 216g ± 60. There was improvement in diastolic function with increase in E '/ A'e E / A and ejection fraction with an increase of 70.2% ± 7.2 to 72.9 ± 6.4%. Conclusion -Obese patients undergoing bariatric surgery showed improvement in physical capacity and in the structure/functioning of the heart. ABCDDV/776RESUMO -Racional -As doenças cardiovasculares representam as complicações mais frequentemente associadas à obesidade. O emagrecimento determina diminuição da pressão arterial e melhora nos parâmetros dos lipídeos e glicose séricos. A perda de peso e sua manutenção reduzem os fatores de risco para doenças cardiovasculares, tornando, reversíveis as alterações cardíacas decorrentes da obesidade. ObjetivoAvaliar o efeito da perda de peso sobre a capacidade física e as alterações estruturais e funcionais do coração de obesos submetidos à procedimento cirúrgico bariátrico. Métodos -Quarenta e três pacientes submetidos à derivação gástrica em Y-de-Roux, foram analisados por eletrocardiograma, teste ergométrico e ecodopplercardiograma no pré-operatório e um ano após a derivação. Na análise estatística utilizaram-se os testes de Wilcoxon, t de Student, Shapiro-Wilk com nível de significância de 5%. Resultados -O peso diminuiu de 116,5 kg ± 21,5 para 80 kg ± 15,9; o IMC de 41,8kg/m2 ± 4,4 para 28,4kg/m2 ± 3,8; a frequência cardíaca reduziu de 77,9 bpm ± 9,6 para 70,9bpm ± 7,8; a pressão sistólica de 130 mmHg ± 20 para 120mmHg ± 10; a diastólica de 80 mmHg ± 10 para 80 mmHg ± 0. O teste ergométrico mostrou aumentos na distância percorrida de 378,9m ± 126,5m para 595m ± 140,4; ...

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“…In fact, Alpert et al 11 studying 62 normotensive morbidly obese patients (at least twice the ideal weight) found an increase in wall thickness in 56% and diastolic diameter in 39% of the sample, resulting in a 64% increase in cardiac mass and dilation of the left atrium in 39% of the cases. …”

Section: Discussionmentioning

confidence: 99%

Contribution of Doppler echocardiography to the evaluation of systolic and diastolic function of obese women versus a control group

Herszkowicz¹,

Barbato²,

Salvi³

et al. 2001

Arq. Bras. Cardiol.

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Effect of weight loss on cardiac chamber size, wall thickness and left ventricular function in morbid obesity

Cited by 187 publications

References 20 publications

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

Emagrecimento e desempenho cardíaco

Contribution of Doppler echocardiography to the evaluation of systolic and diastolic function of obese women versus a control group

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