Abstract:Introduction: Insufficient agreement between results of various in-house and commercial thrombin generation (TG) assays complicates TG adoption and use. This can be caused by different assay variables, for example, volumes and concentrations of reagents. Although most modern assays employ the same fluorogenic thrombin substrate Z-Gly-Gly-Arg 7-amino-4-methylcoumarin (ZGGR-AMC), the excitation (Ex) and emission (Em) wavelengths used for fluorescence signal measurements can be different.
Objectives:We sought to … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.