Effect of vulvomucosal injection of PGF2α at insemination on subsequent fertility and litter size in pigs under field conditions

Peña, Fernando J.; Domínguez, Juan Carlos Castillo; Alegre, B.; Peláez, J.

doi:10.1016/s0378-4320(98)00083-9

Cited by 17 publications

(9 citation statements)

References 14 publications

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“…What has not been adequately addressed is the potential source of the variable efficacy. Previous authors presenting data for a positive effect of PGF on sow fertility have attributed it to an effect on sperm transport, and possibly on time of ovulation (Pena et al. 1998, 2000; Horvat and Bilkei 2003; Kos and Bilkei 2004).…”

Section: Discussionmentioning

confidence: 99%

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Effect of Cloprostenol Treatment at Artificial Insemination on Sow Fertility

Kirkwood¹,

Rensis²,

P³

et al. 2007

Reprod Domestic Animals

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In two experiments, we examined the effect of administration of cloprostenol at artificial insemination on fertility of multiparous sows. Lactation length was 21 days and only sows exhibiting estrus by 7 days after weaning were included. Cloprostenol was administered by IM injection (175 microg; n=126) or supplemented in the semen dose (525 microg; n=129). Control sows (n=130) received no hormone. In either experiment, there was no effect of any treatment on subsequent litter sizes. In experiment 1, there was no effect of treatment on farrowing rate, but in experiment 2, farrowing rate was higher (p < 0.05) in sows receiving cloprostenol by injection. Taken together, these results indicate no consistent effect of cloprostenol administration by intramuscular injection or by inclusion in the semen dose on sow fertility and so its routine use is not warranted.

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Section: Discussionmentioning

confidence: 99%

“…However, exogenous PGF administered either by injection (Pena et al. 1998) or included in the semen dose increased farrowing rates and, more variably, also litter size (Pena et al. 1998, 2000; Horvat and Bilkei 2003; Kos and Bilkei 2004).…”

Section: Introductionmentioning

confidence: 99%

Effect of Cloprostenol Treatment at Artificial Insemination on Sow Fertility

Kirkwood¹,

Rensis²,

P³

et al. 2007

Reprod Domestic Animals

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“…Interestingly, this treatment significantly improved farrowing rates, during the lowfertility season in the summer (78% vs. 54%). However, in these same sows, litter size was also statistically increased in sows administered PGF 2a throughout the entire year (10.80 vs. 9.14 in the summer, and 11.16 vs. 9.99 the rest of the year) (Pena et al 1998). The authors hypothesized that the PGF 2a mimicked and replaced the physical and pheromone signals sows usually receive during boar contact and elicited a similar contractile effect on the uterus.…”

Section: Introductionmentioning

confidence: 92%

“…Cloprostenol is a commercially available synthetic analogue of PGF 2a that induces luteolysis followed by oestrus and ovulation (Moeljono et al 1976). The ovarian follicles respond to PGF 2a by producing their own prostaglandins, which in turn activate collagenase and elastase, which are involved in ovulation (Pena et al 1998). The effect of PGF 2a on conception and farrowing rates was examined in a study where PGF 2a was injected into the lips of the vulva, at the time of AI (in the absence of a boar).…”

Section: Introductionmentioning

confidence: 99%

Are Pharmacological Interventions Between Conception and Birth Effective in Improving Reproductive Outcomes in North American Swine?

Wessels

Khalaj

Kridli

et al. 2014

Reprod Domestic Animals

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The objective of this review is to evaluate the effectiveness of using pharmacological compounds on reproductive outcomes, particularly litter size, in North American swine. While the opportunity to improve reproduction in North American pigs exists, numerous hurdles need to be overcome in order to achieve measureable results. In the swine industry, the majority of piglet losses are incurred during pregnancy and around farrowing. Over the last 20 years, a reduction in losses has been achieved through genetic selection and nutritional management; however, these topics are the focus of other reviews. This review will evaluate attempts to improve litter size by reducing losses at various stages of the reproductive process, from the time of conception to the time of farrowing, using pharmacological compounds. Generally, these compounds are used to either alter physiological processes related to fertilization, embryonic attachment or uterine capacity, etc., or to facilitate management aspects of the breeding females such as inducing parturition. Although some of the pharmacological agents reviewed here show some positive effects on improving reproductive parameters, the inconsistent results and associated risks usually outweigh the benefits gained. Thus, at the present time, the use of pharmacological agents to enhance reproduction in North American swine may only be recommended for herds with low fertility and presents an avenue of research that could be further explored.

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“…The problem of seasonal infertility in pigs is observed especially, but not only, in moderate climates (1). Research projects on the addition of hormones to semen during summer infertility come from the last decade (10)(11)(12)(13)(14). They mainly focus on using progestagens, gonadotropins, oxytocin, and prostaglandin and its derivatives.…”

Section: Introductionmentioning

confidence: 99%