Abstract:The purpose of this study was to clarify the effect of vitamins K, D, and C supplementation on the development of osteopenia in calcium-deficient young female rats. Fourty nine female Sprague-Dawley rats, 6 weeks of age, were randomized into 7 groups with 7 rats in each group: Baseline control, 0.5% (normal) calcium diet, 0.1% (low) calcium diet, 0.1% calcium diet + vitamin K (30 mg / 100g food intake), 0.1% calcium diet + vitamin D (25 µg / 100 g food intake), 0.1% calcium diet + vitamin C (1.5 g / 100 g food… Show more
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