Effect of Vitamin E and Zinc Supplementation on Energy Metabolites, Lipid Peroxidation, and Milk Production in Peripartum Sahiwal Cows

Abstract

The study was conducted to evaluate the effect of vitamin E and zinc supplementation on energy metabolites, lipid peroxidation, and milk production in peripartum Sahiwal cows. For this, thirty-two pregnant dry Sahiwal cows were selected at sixty days prepartum and divided into four groups viz control, T1, T2, and T3 of eight each. Group T1 were supplemented with zinc at 60 ppm/d/cow, group T2 were supplemented with vitamin E at 1,000 IU/d/cow and group T3 were supplemented with combination of vitamin E at 1,000 IU/d/cow and zinc at 60 ppm/d/cow during d 60 prepartum to d 90 postpartum. Blood samples were collected on d −60, −45, −30, −15, −7, −3, 0, 3, 7, 15, 30, 45, 60, 90, and 120 with respect to day of parturition and analysed for glucose, non esterified fatty acid, and thiobarbituric acid reactive substance. Body condition score was maintained significantly better (p<0.05) in T3 than in the control, T1 and T2 groups. Overall glucose level was higher (p<0.05) in T3 than control, T1, and T2 groups. Levels of nonesterified fatty acid, and thiobarbituric acid reactive substance were lower (p<0.05) in T3 than control, T1, and T2 groups. Milk yield was higher (p<0.05) in T3 than control, T1, and T2 groups. In conclusion, the present study indicated that the supplementation of vitamin E and zinc in peripartum Sahiwal cows enhanced milk production by reducing negative energy balance.

Effect of zinc supplementation on hormonal and lipid peroxidation status of peri-parturient Karan Fries cows during heat stress condition

“…This is might be due to the fact that zinc may play a key role in suppression of free radicals because it is a cofactor of the main anti-oxidative enzyme Cu-Zinc-SOD and it also inhibits the NADPH-dependent lipid peroxidation ( (Prasad et al, 2002).Our results are in agreement with Chandra et al (2013) reported higher TBARS concentration in pregnant crossbred cows during summer (6.23 ± 0.02nm) compared to winter (5.37 ± 0.07nmol). Similar to our result Chandra et al (2013) reported that TBARS level is significantly (P<0.05) lower in zinc supplemented groups (3.01 vs. 2.46 µM). Nagalakshmi et al (2012) supplemented zinc carbonate in female rats and found that lipid peroxidation was significantly (P<0.01) lower in supplemented groups as compared to control.…”

Investigation changes in production, some blood hormones, and metabolites, serum and colostrum IgG of calves of Holstein cows fed with two levels of zinc supplement in transitional period

“…Body condition was scored with 1-5 scales based on Wildman et al (1982), and supplemented zinc had no effect on BCS and this is in agreement with Cope et al (2009), Chandra et al (2013) and Nayeri et al (2014). In addition, organic or inorganic forms of zinc does not seem to have effect on BCS (Cope et al 2009;Nayeri et al 2014).…”

The effect of additional supplementation of vitamin E and zinc on endocrine and metabolic changes in dairy cows during peripartal period

“…However, decreased DMI around calving may also be a reason for declining glucose during this period (BELL and BAUMAN, 1997). Vitamin E and Zn supplementation improved the plasma concentration of glucose, which was also reported by CHANDRA et al (2013) in Sahiwal cows. The body condition of cows declines around calving and substantial rises in NEFA the in blood reveals body tissue mobilization (BOYLE et al, 2006).…”