Effect of Vitamin and Mineral Supplementation on Intelligence of a Sample of Schoolchildren

Benton, David; Roberts, Gwilym

doi:10.1016/s0140-6736(88)92720-1

Cited by 168 publications

(77 citation statements)

References 15 publications

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“…The striking difference between the vitamin A intakes may reflect the fact that the school studied was in a lower income area of Dundee, as the DHSS (1989) data for the UK as a whole show lower intakes of vitamin A in lower socio-economic groups. Third, when the data on intake of fourteen micronutrients is compared with the reported nutrient intakes of children in the Welsh study (Benton & Roberts, 1988), the Dundee children in the present study are seen to have similar or lower intakes of all micronutrients except for Fe in girls and Ca in both boys and girls. If the nutrient intake data of these children is to form the basis of dietary advice, it is useful to analyse the data in terms of the proportion of nutrients provided by different food groups.…”

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confidence: 56%

“…More recently the possibility of inadequacy of the diet of schoolchildren has been brought to the attention of scientists and the public by the publication of a report suggesting that low vitamin and mineral intake may impair mental function (Benton & Roberts, 1988). It seems as important now as ever before to be able to assess the adequacy of schoolchildren's diets and to identify possible health risks associated with current dietary practices.…”

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confidence: 99%

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Nutrient intake in schoolchildren: some practical considerations

McNeill¹,

Davidson²,

Morrison³

et al. 1991

Proc. Nutr. Soc.

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confidence: 56%

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confidence: 99%

Nutrient intake in schoolchildren: some practical considerations

McNeill¹,

Davidson²,

Morrison³

et al. 1991

Proc. Nutr. Soc.

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“…A LTHOUGH STUDIES HAVE sought to improve mental and psychomotor development in children through protein energy 1 and multivitamin child supplements, [2][3][4] few have examined the effect of maternal supplements on infant development. Nutritional deficiencies are common in children in developing countries.…”

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confidence: 99%

Effect of Maternal Multivitamin Supplementation on the Mental and Psychomotor Development of Children Who Are Born to HIV-1–Infected Mothers in Tanzania

et al. 2006

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OBJECTIVES. To determine the association between maternal multivitamin supplementation and the mental and psychomotor development of children who are born to HIV-1-infected mothers in Tanzania, as secondary endpoints in a randomized trial that investigated the effect of maternal multivitamin supplementation on HIV-1 vertical transmission and progression.METHODS. The Bayley Scales of Infant Development, 2nd Edition, were administered at 6, 12, and 18 months of age to a subset of children (N ϭ 327). We assessed the effect of vitamin A and multivitamin (vitamins B, C, and E) supplementation using linear regression models and Cox proportional hazard models for the Mental Development Index, the Psychomotor Development Index, and raw scores separately.RESULTS. Multivitamin supplementation was associated significantly with a mean increase in Psychomotor Development Index score of 2.6 (95% confidence interval: 0.1-5.1). Multivitamins were also significantly protective against the risk for developmental delay on the motor scale (relative risk: 0.4; 95% confidence interval: 0.2-0.7) but not on the Mental Development Index. Vitamin A supplementation had no significant effect on these outcomes.CONCLUSIONS. Maternal multivitamin supplements provide a low-cost intervention to reduce the risk for developmental delays among infants who are born to HIVpositive mothers in developing countries. McGRATH, et al by guest on May 11, 2018 http://pediatrics.aappublications.org/ Downloaded from A LTHOUGH STUDIES HAVE sought to improve mental and psychomotor development in children through protein energy 1 and multivitamin child supplements, 2-4 few have examined the effect of maternal supplements on infant development. Nutritional deficiencies are common in children in developing countries. 5 In 1996, 43% of preschool Tanzanian children were stunted (low height for age). 6 Vitamin A, iodine, and iron deficiencies are also prevalent. 7-9 Pepping et al 8 found that vitamin A deficiency was a significant problem in Tanzania, with 1.5% of the preschool age children whom they surveyed having xerophthalmia and 1.6% having Bitot's spots. In addition, children are have HIV-1 infection; antenatal HIV-1 seroprevalence has been ϳ12% since 1995 in Dar es Salaam. 10 Because multivitamin deficiencies are associated with faster HIV disease progression in adults 11 and higher risk for infant morbidity, 12 they may have a negative impact on the mental and psychomotor development of the child.Daily consumption of multivitamin supplements by HIV-1-infected pregnant women has been shown to delay significantly the progression of HIV disease. 13 Multivitamin supplements also resulted in significant reductions in the risk for low birth weight (LBW), severe preterm birth, and fetal loss and improved the immunologic profile of the mothers and increased their hemoglobin concentrations. 14 Vitamin A supplementation during pregnancy has also been shown to reduce the risk for preterm delivery among HIV-infected women. 15 Baylin et al 16 demonstrated that vit...

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“…For the beneficial effects of vitamin and mineral supplementation on intelligence the evidence is so scanty and preliminary that it would probably not have been accepted for publication in any more rigorous scientific field (Bates et af. 1988; Benton & Roberts, 1988;Emery et al 1988;Naismith et al 1988); whereas in the case of Pb there is only one recent study (Fulton et af. 1987) amongst many other very careful ones (Medical Research Council, 1988u,b) which shows any significant correlation at all between exposure to Pb and scores in various estimations of I.Q.…”

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confidence: 99%

Early nutrition and later achievement

Dobbing

1990

Proc. Nutr. Soc.

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Effect of Vitamin and Mineral Supplementation on Intelligence of a Sample of Schoolchildren

Cited by 168 publications

References 15 publications

Nutrient intake in schoolchildren: some practical considerations

Nutrient intake in schoolchildren: some practical considerations

Effect of Maternal Multivitamin Supplementation on the Mental and Psychomotor Development of Children Who Are Born to HIV-1–Infected Mothers in Tanzania

Early nutrition and later achievement

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