Effect of vertebrobasilar dolichoectasia on endovascular therapy in acute posterior circulation infarction

Abstract

prognostic effect of puncture-to-recanalization time on the probability of mortality within 90 days in EVT-treated patients with VBD was significant {adjusted odds ratio, 1.008 [95% confidence interval (1.001-1.015)]}. Conclusion:Endovascular therapy is safe and feasible in patients with acute posterior circulation stroke and VBD. The puncture-to-recanalization time is important for predicting the prognosis of EVT-treated patients with VBD.

Successful endovascular reconstruction of symptomatic vertebrobasilar dolichoectasia using multiple Leo stents and nondominant vertebral artery occlusion: a case report

“…The endovascular approach to VBD reconstruction depended on the clinical manifestation of VBD, either ischemic, hemorrhagic, or compression. 1,4 This patient had hemorrhagic symptoms due to VBD rupture, which resulted in the decision to perform VBD reconstruction using multiple scaffolding Leo stents in combination with nondominant vertebral artery occlusion. 1 The stents were deployed along the VBD with anchors at both proximal and distal normal vascular sites.…”

“…2,3 While it may be asymptomatic, VBD may manifest in 46.8% subjects as vascular or compressive symptoms, including ischemic stroke, and subarachnoid hemorrhage, cranial nerve compression, brainstem compression, hydrocephalus, cerebellar dysfunction, and central sleep apnea. 1,4 Wolters et al studied 375 VBD subjects and reported that the 5-year new event included ischemic stroke (17.6%), brainstem compression (10.3%), transient ischemic attack (10.1%), spontaneous intracerebral hemorrhage (4.7%), hydrocephalus (3.3%), and subarachnoid hemorrhage (2.6%). Another study by Passero and Rossi (2008) reported that of 156 subjects with VBD and median follow-up of 11.7 years, 43% had progression of VBD and approximately 60% experienced at least one symptomatic event.…”

“…5,6 Some techniques for endovascular reconstruction included multiple stent reconstruction, distal vertebral artery occlusion, aneurysm coiling, and thrombectomy (for VBD with acute ischemic stroke). [1][2][3][4][5] This study aimed to report symptomatic VBD of subarachnoid hemorrhage, brainstem compression, and hydrocephalus who was successfully treated with combined endovascular treatment of multiple scaffolding Leo stent and nondominant vertebral artery coiling.…”

Acute Basilar Artery Occlusion Induced by Rapidly Progressive Thrombosis in Vertebrobasilar Dolichoectasia

“…Acute thrombosis can be treated with intravenous thrombolysis or thrombectomy for occlusive thrombus, but the efficacy remains uncertain. [3][4][5]…”

Study on the relationship between vertebrobasilar dolichoectasia and posterior cranial fossa space

“…VBD mainly shows abnormal extension, expansion and bending of vertebral basilar artery, which can compress brain tissues such as cranial nerve, cerebellum and brain stem, showing changes such as cerebral nerve stimulation and posterior circulation ischemia. Although hemorrhagic cerebrovascular disease caused by VBD is relatively rare, but once hemorrhagic stroke occurs, its symptoms are serious and the prognosis is worse [ [5] , [6] , [7] , [8] , [9] , [10] ]. At present, there are few studies on the etiology of VBD.…”