Diets supplemented with enzymatically produced structured lipid (SL) containing n-3 polyunsaturated fatty acids (eicosapentaenoic and docosahexaenoic) and cap ylic acid or soybean oil (1 6.7 g/lOO g) were fed to 4 to 6 week old female mice for 2 I days. The effect of the diets on serum lipids (HDLcholesterol, LDL-cholesterol, total cholesterol, triacylglycerol) and glucose concentrations were determined. The concentration of total cholesterol (49%), LDL cholesterol (35.4%) and triacylglycerol (S3.2%) were signijkantly lowered in SLfed group. The body weight gain in mice fed the soybean oil diet (control group) was signijicantly (p<0.05) greater than that in mice fed the SL diet after 21 days.