Effect of varicocelectomy on the plasma oxidative stress parameters

Cervellione, Raimondo M.; Cervato, Giovanna; Zampieri, Nicola; Corroppolo, Michele; Canoglio, Francesco; Cestaro, Benvenuto; Ottolenghi, A.

doi:10.1016/j.jpedsurg.2005.11.018

Cited by 33 publications

(14 citation statements)

References 10 publications

(13 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Then the process becomes autocatalytic and results in formation of hydroperoxides and other products, such as malonaldehyde (MDA), an alkylating agent with the ability to covalently bind to nucleophilic groups of DNA, peptides and proteins, modifying their molecular function (32,33). Moreover, Yesilli et al (34) and Cervellione et al (35) observed high levels of MDA in men with varicocele when compared with healthy men.…”

Section: Discussionmentioning

confidence: 99%

Sperm nuclear DNA fragmentation and mitochondrial activity in men with varicocele

Blumer

Fariello

Restelli

et al. 2008

Fertility and Sterility

140

110

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Sperm nuclear DNA fragmentation and mitochondrial activity in men with varicocele

Blumer

Fariello

Restelli

et al. 2008

Fertility and Sterility

140

110

View full text Add to dashboard Cite

“…After surgery they significantly decreased, again suggesting that surgical varicocelectomy with a venous shunt construction reduces OS. The study highlights that OS is present in children and adolescents with VAR [36]. …”

Section: Effects Of Surgical Treatmentmentioning

confidence: 99%

Biochemical Alterations in Semen of Varicocele Patients: A Review of the Literature

Mancini

Festa

Raimondo

et al. 2012

Advances in Urology

View full text Add to dashboard Cite

Oxidative stress is a mechanism underlying different kinds of infertility in human males. However, different results can be observed in relation to the method used for its evaluation. Varicocele patients show a number of biochemical abnormalities, including an altered distribution of coenzyme Q between seminal plasma and sperm cells and also an apparent defect in the utilization of antioxidants. Moreover, an influence of systemic hormones on seminal antioxidant system was observed too. Finally, the effects of surgical treatment on oxidativestress indexes and the possible usefulness of some medical therapies, like coenzyme Q supplementation, are discussed. In conclusion, published data show a role of oxidative stress in varicocele-related male infertility, but at present we do not know the precise molecular mechanisms underlying these phenomena.

show abstract

“…Several studies have demonstrated the role of oxidative stress in men with varicocele and infertility (4,5). Varicocelectomy has recently been shown to reduce seminal oxidative stress in infertile men (6,7).…”

mentioning

confidence: 99%

Right subclinical varicocele: how to manage in infertile patients with clinical left varicocele?

Elbendary

Elbadry

2009

Fertility and Sterility

View full text Add to dashboard Cite

Effect of varicocelectomy on the plasma oxidative stress parameters

Cited by 33 publications

References 10 publications

Sperm nuclear DNA fragmentation and mitochondrial activity in men with varicocele

Sperm nuclear DNA fragmentation and mitochondrial activity in men with varicocele

Biochemical Alterations in Semen of Varicocele Patients: A Review of the Literature

Right subclinical varicocele: how to manage in infertile patients with clinical left varicocele?

Contact Info

Product

Resources

About