Effect of Varicocelectomy on Testicular Volume in Children and Adolescents: A Meta-analysis

Li, Fuping; Chiba, Koji; Yamaguchi, Kensei; Okada, Keisuke; Matsushita, Kei; Ando, Motomi; Yue, Huanxun; Fujisawa, Masato

doi:10.1016/j.urology.2012.02.022

Cited by 51 publications

(34 citation statements)

References 30 publications

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“…[28] In various current series 73-90% catch-up growth rates have been detected. [20][21][22] In our study 70% catch-up growth rate was detected. However, Cayan et al [29] observed improvement in previously low sperm counts of 15-19-year-old men after varicocelectomy, while testicular catch-up growth was not observed in these patients.…”

Section: Discussionsupporting

confidence: 52%

“…In various novel series catch-up growth rates have varied between 73, and 90 percent. [20][21][22] In studies performed on the impact of surgical method on catch-up growth rate, any effect of surgical method on testicular catch-up rate could not be detected. [13,23] Recently, Shiraishi et al [23] , performed subinguinal, and high-ligation microsurgical varicocelectomy, and indicated 70, and 78% catch-up growth rates during 24 months of the follow-up period, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…[9] Some investigators have reported recovery of testicular development, and sperm dysfunction after varicocelectomy. [10,20,21] Sinanoğlu et al [10] followed up 39 adolescents with varicocele at 3 month-intervals after varicocelectomy just by calculating testicular volumes. As a result of an average followup of 39 months, they reported catch-up growth in 90% of the cases with ipsilateral testicular atrophy.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of testicular catch-up growth in adolescent microsurgical varicocelectomy

Bedir¹,

Keskin²,

Karabakan³

et al. 2017

Turkish Journal of Urology

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Objective: The incidence of varicocele is approximately 15% in adolecent men. Early treatment with varicocele is aimed to resolve testicular hypotrophy and ensure catch-up growth. The aim of this study was to evaluate ipsilateral catch-up growth rates relative to contralateral testicular growth in adolescents with varicocele undergoing microsurgical subinguinal varicocelectomy. Material and methods:Fifty adolescents with unilateral grade 2-3 varicoceles were included in the study. All patients underwent microsurgical subinguinal left varicocelectomies performed by the same experienced surgeon. All patients were evaluated clinically and using orchidometric measurements to define the grade of varicocele and testicular volume at presentation and follow-up. The number of internal and external spermatic veins, testicular arteries and lymphatic vessels preserved during the subinguinal microsurgical varicocelectomy were recorded. The mean follow-up period was 26 months (range 6-48 months).Results: At presentation, mean patient age was 12.9±2.1 years. Mean testicular preoperative volumes were 7.1±4.3 mL for the right and 5.4±3.4 mL for the left testis. There were significant differences between mean volumes of the right and left testis (p= 0.002). At the final postoperative follow-up visit, mean testicular volumes were 10.8±5.1 mL (range 3-25) for the right and 9.9±4.3 mL (range 2-20) for the left, and the difference between the right and left testicular volumes was insignificant (p= 0.47). In our series, catch-up growth was observed in 70% (35/50) of our patients. Conclusion:Adolescent varicocelectomy is associated with a higher percentage of patients showing testicular catch-up growth. In our study, similarly to the available literature the catch-up growth rate was found as 70% and observed to have positive effects of adolescent varicocelectomy on testicular growth.

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Section: Discussionsupporting

confidence: 52%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of testicular catch-up growth in adolescent microsurgical varicocelectomy

Bedir¹,

Keskin²,

Karabakan³

et al. 2017

Turkish Journal of Urology

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“…[28,29] However, testicular volumes may not increase significantly after varicocele repair in patients aged >14 years. [13] Studies suggest that varicocele repair in the adolescents significantly increases sperm parameters including sperm concentration, sperm motility and total motile sperm count, postoperatively.…”

Section: Postoperative Resultsmentioning

confidence: 99%

“…Varicocele repair results in a significant increase in testicular volumes and consistency, and testicular catch-up growth has been occured in 53-94% of adolescents, postoperatively. [28,29] However, testicular volumes may not increase significantly after varicocele repair in patients aged >14 years (grade C). Repair of the adolescent varicocele may improve semen parameters and serum hormone values regardless of testicular volumes (grade C).…”

Section: Paternity Situation After Treatment Of Adolescent Varicocelementioning

confidence: 99%

Update on the novel management and future paternity situation in adolescents with varicocele

Çayan

Bozlu

Akbay

2017

Turkish Journal of Urology

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Varicocele is a progressive disease, and the incidence of varicocele and varicocele related testicular hypotrophy increases with puberty. This review updates novel management and future paternity potential in adolescents with varicocele. Main goal of treatment of the adolescent varicoceles is preservation of fertility. Current recommendations for adolescent varicocele repair are testicular hypotrophy (>2 mL or >20%) on the affected side and/or impaired spermatogenesis in the post-pubertal period. The best treatment modality for adolescent varicocele should include elimination of the varicocele with lower complication rates. Microsurgical varicocelectomy techniques have been shown to result in fewer recurrences and postoperative complications than conventional varicocelectomy in adolescents. We conducted a meta-analysis, including 2 studies with the control groups, and reporting paternity situation after varicocele treatment. In this metaanalysis, varicocele repair increases paternity rate 2.42 times with a p value of 0.000. Adolescents with varicocele and their families should be counselled in the light of these findings.

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Varicocele

Subramaniam¹

2015

Pediatric Urology

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Effect of Varicocelectomy on Testicular Volume in Children and Adolescents: A Meta-analysis

Cited by 51 publications

References 30 publications

Evaluation of testicular catch-up growth in adolescent microsurgical varicocelectomy

Evaluation of testicular catch-up growth in adolescent microsurgical varicocelectomy

Update on the novel management and future paternity situation in adolescents with varicocele

Varicocele

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