Effect of Vanillin on Emotional Stress and Pain-Related Behaviours Induced by Experimental Tooth Movement in Rats
Tingting Wu,
Wenning Wu,
Shiyu Jin
et al.
Abstract:Background
Pain is a common symptom of orthodontic treatment. Therefore, this study aimed to determine the effect of vanillin on emotional stress and pain-related behaviours induced during tooth movement by observing the behaviours of orthodontic rats and to provide a therapeutic basis for the discomfort caused by orthodontic treatment.
Methods
A 75 g orthodontic force was applied via an orthodontic appliance to the left maxillary incisors and first molars of 200–250 g male Sprague-Dawley rats. The rats were… Show more
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