Effect of Vanadium Administration on Coenzyme Q Metabolism in Rats

Reprotoxic and genotoxic studies of vanadium pentoxide in male mice

“…Vanadate is a potent inhibitor of the dynein ATPase [29-3 11, and blocked the vibration completely at micromolar concentrations. On the other hand, it is known that vanadium compounds uncouple mitochondnal oxidative phosphorylation in liver homogenates in vitro [32] and inhibit succinic dehydrogenase [33] resulting in the depletion of ATP energetic stores [34].…”

Baseline risk assessment of ground water contamination at the Uranium Mill Tailings Sites near Rifle, Colorado. Revision 2

“…Metabolic effects include interference with the biosynthesis of cystine and cholesterol, depression and stimulation of phospholipid synthesis, and at higher concentrations, inhibition of serotonin oxidation. Other effects of vanadium on mammalian metabolism include depression of phospholipid synthesis (Snyder and Cornatzer, 19581, reduction of coenzyme Q levels in mitochondria (Aiyar and Sreenivasan, 1961 ), and stimulation of monoamine oxidase, which oxidizes serotonin (Perry et al, 1955).…”

Baseline risk assessment of ground water contamination at the uranium mill tailings site near Riverton, Wyoming. Revision 1

“…Metabolic effects include interference with the biosynthesis of cystine and cholesterol, depression and stimulation of phospholipid synthesis, and at higher concentrations, inhibition of serotonin oxidation. Other effects of vanadium on mammalian metabolism include depression of phospholipid synthesis (Snyder and Cornatzer, 1 9581, reduction of coenzyme 0 levels in mitochondria (Aiyar and Sreenivasan, 1961 1, and stimulation of monoamine oxidase, which oxidizes serotonin (Perry e t al., 1955).…”