2023
DOI: 10.3389/fneur.2023.1258854
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Effect of vagus nerve stimulation against generalized seizure and status epilepticus recurrence

Yasushi Iimura,
Hiroharu Suzuki,
Takumi Mitsuhashi
et al.

Abstract: ObjectiveVagus nerve stimulation (VNS) is a palliative surgery for drug-resistant epilepsy. The two objectives of this study were to (1) determine the seizure type most responsive to VNS and (2) investigate the preventive effect on status epilepticus (SE) recurrence.MethodsWe retrospectively reviewed 136 patients with drug-resistant epilepsy who underwent VNS implantation. We examined seizure outcomes at 6, 12, and 24 months following implantation of VNS as well as at the last visit to the Juntendo Epilepsy Ce… Show more

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Cited by 3 publications
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“…In our case series, no recurrence of SE was reported. A recent study [26] evaluated the efficacy of VNS through a follow-up of approximately 69 months in 125 patients from 14 to 44 years of age with drug-resistant epilepsy. In total, 56% of patients showed at least a 50% reduction in seizure frequency; however, one element that seems to predict which subjects will be non-responders is a history of SE prior to VNS implantation.…”
Section: Discussionmentioning
confidence: 99%
“…In our case series, no recurrence of SE was reported. A recent study [26] evaluated the efficacy of VNS through a follow-up of approximately 69 months in 125 patients from 14 to 44 years of age with drug-resistant epilepsy. In total, 56% of patients showed at least a 50% reduction in seizure frequency; however, one element that seems to predict which subjects will be non-responders is a history of SE prior to VNS implantation.…”
Section: Discussionmentioning
confidence: 99%