Effect of Vagal and Sympathetic Stimulation and Ablation on Gastric Blood Flow

Peter, Edward T.; Nicoloff, Demétre M.; Leonard, Arnold S.; Walder, Arnold I.; Wangensteen, Owen H.

doi:10.1001/jama.1963.63700120006009b

Cited by 44 publications

(5 citation statements)

References 2 publications

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“…This discrepancy was explained by the difference of the period after vagotomy. Namely, gastric mucosal blood flow decreased soon after vagotomy as Peter et al (1963) or Bell and Battersby (1968) reported, but returned to the same level in 2 to 6 weeks after vagotomy as Delaney (1967) or Levine et al (1981) reported. Our data on gastric mucosal blood flow were measured at 2 weeks after vagotomy, so there was no significant difference between the control group and the vagotomy group.…”

Section: Discussionmentioning

confidence: 76%

“…These data are comparable with Delaney's report (1967) or Levine's report (1981) which stated that vagotomy brought no changes in gastric mucosal blood flow in experimental studies. On the other hand, Peter et al (1963) or Bell and Battersby (1968) reported that vagotomy decreased gastric mucosal blood flow. This discrepancy was explained by the difference of the period after vagotomy.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Acute gastric ulceration in rats with obstructive jaundice with special reference to gastric mucosal blood flow.

Sasaki

Konno

Kamiyama

et al. 1987

Tohoku J. Exp. Med.

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Section: Discussionmentioning

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Acute gastric ulceration in rats with obstructive jaundice with special reference to gastric mucosal blood flow.

Sasaki

Konno

Kamiyama

et al. 1987

Tohoku J. Exp. Med.

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“…Canine blood flow in the gastroepiploic and splenic arteries has been measured by an electromagnetic flowmeter. Using this technique, truncal vagotomy was found to cause an immediate reduction of 30% in total gastric flow [15]. Ballinger et al [9] also used the electromagnetic flowmeter in their studies.…”

Section: Discussionmentioning

confidence: 99%

Gastric ulcers following vagotomy in piglets

1978

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Acute gastric ulceration occurred within 2 days of highly selective vagotomy (HSV) or truncal vagotomy and pyloroplasty (VP) in 24 of 38 piglets (63%). Twenty-three control animals with gastric and nongastric sham operations or anesthesia alone had normal stomachs when examined after 2 days. Microspheres labeled with various isotopes were injected sequentially to study a possible hemodynamic etiology of postvagotomy ulceration. At intervals of 1, 3, and 5 hours after vagotomy or a control operation, mierospheres were injected into the left atrium. Animals were sacrificed 48 hours later and stomachs excised, inspected, divided into 1-2 cm squares and counted for radioactivity. Blood flow to squares, gastric regions, and total stomach was calculated for each isotope (time interval). Total flow in squares with and without ulcers was similar, but the distribution of flow between mucosa and muscle varied. In HSV piglets, mucosal perfusion decreased 41% in ulcerated squares and 21% in normal areas. Muscle flow was increased 95% in ulcerated squares and 177% in normal areas. In VP piglets, mucosal perfusion was reduced 45% in squares with ulcers and 21% in normal squares, while muscle flow increased 18% in ulcerated samples and 194% in normal areas. Vagotomy appears to cause acute gastric ulceration in piglets by diverting gastric blood flow from mucosa to muscle.Acute gastric ulceration in piglets follows both hemorrhagic [1, 2] and endotoxic shock [3]. Gastric lesions in each instance are similar histologically and occur within 2 days of shock. This ulceration can be prevented by exclusion of bile [4] and by pretreatment with cholestyramine or methylpredniso-

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“…5,6 Metodologias visando a elucidação de aspectos relacionados à capacidade de perfusão sangüínea na mucosa do estômago são amplamente empregadas em experimentos com humanos e com animais de diferentes espécies. 7,8,9,10,11 Nos eqüinos, a ocorrência de lesões na mucosa gástrica assume grande importância, especialmente em animais submetidos a treinamento intensivo. Cerca de 70 a 85% destes animais podem apresentar o problema em diferentes graus de severidade.…”

Section: Introductionunclassified

Distribuição da artéria gástrica esquerda e artérias gástricas curtas na superfície do estômago de eqüinos e relação com a área superficial do órgão

Alonso

Resende

Duboc³

et al. 2008

Braz. J. Vet. Res. Anim. Sci.

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Vasos responsáveis pelo suprimento sangüíneo do estômago originam-se da artéria celíaca, primeiro ramo da aorta abdominal, localizada na região do hiato aórtico. Assim, dirigem-se à superfície do estômago as artérias gástricas esquerda e direita, as artérias gastroepilóicas esquerda e direita e as artérias gástricas curtas. Apesar de bem conhecidas as origens destes vasos, informações a respeito do comportamento dos mesmos ao atingirem a superfície do estômago ainda são escassas. O fluxo sangüíneo na parede do estômago exerce importante papel nos mecanismos de defesa da mucosa gástrica. Eqüinos em treinamento intensivo apresentam alta freqüência de ocorrência de lesões ulcerativas na mucosa do estômago, tornando as pesquisas sobre vascularização sangüínea deste órgão com grande significado prático na compreensão dos mecanismos relacionados à proteção da mucosa gástrica. O objetivo deste trabalho foi avaliar alguns aspectos relacionados à distribuição arterial na superfície do estômago de eqüinos adultos, sem raça definida e destinados a abate. Utilizaram-se estômagos oriundos de 15 machos e 15 fêmeas. A área superficial do estômago foi mensurada com software de análise de imagens e os dados correlacionados ao número de ramos avaliados. Observou-se reduzida participação da artéria gástrica esquerda na irrigação da curvatura menor do estômago. Estes achados justificam estudos relacionados à particularidades anatômicas da região da curvatura menor do estômago de eqüinos, em trabalhos futuros.

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Effect of Vagal and Sympathetic Stimulation and Ablation on Gastric Blood Flow

Cited by 44 publications

References 2 publications

Acute gastric ulceration in rats with obstructive jaundice with special reference to gastric mucosal blood flow.

Acute gastric ulceration in rats with obstructive jaundice with special reference to gastric mucosal blood flow.

Gastric ulcers following vagotomy in piglets

Distribuição da artéria gástrica esquerda e artérias gástricas curtas na superfície do estômago de eqüinos e relação com a área superficial do órgão

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