Effect of vaccination on experimental infection with Bordetella bronchiseptica in dogs

Abstract

Parenterally and intranasally administered vaccines containing B bronchiseptica may provide substantial protection from clinical signs of respiratory tract disease associated with infection by this bacterium. Administration of both types of vaccines in sequence afforded the greatest degree of protection against disease.

Infectious Tracheobronchitis

“…[1][2][3][4][5] Although canine adenovirus-2 (CAV-2), canine distemper virus (CDV), reovirus, and canine herpesvirus are all capable of infecting the upper respiratory tract of dogs and causing acute-onset cough, their roles in the etiopathogenesis of ITB are less important than those of B. bronchiseptica and CPiV. In fact, various bacteria and viruses, acting either alone or in combination, contribute to the various signs associated with canine ITB.…”

Prevalence of canine infectious respiratory pathogens in asymptomatic dogs presented atUSanimal shelters

“…When co‐infections are involved, CIRD can progress to a more severe and protracted disease (Erles et al , Ettinger & Kantrowitz , Ellis et al , Buonavoglia & Martella ). Although multi‐factorial infection often occurs in CIRD, Bordetella bronchiseptica by itself has been found to cause clinical respiratory disease, (McCandlish et al , Ellis et al ), and is generally considered to be the single most prevalent and important CIRD pathogen despite its usual role as a commensal agent (Keil & Fenwick 2000, Ford ).…”

Occurence of Bordetella bronchiseptica in domestic cats with upper respiratory tract infections

“…A detailed determination of which Bordetella genotypes are the most common in cats and dogs may be of value in the preparation of a vaccine with antigens containing complete cells or proteins of these particular microorganisms. Correct antigen selection has a decisive effect on the effectiveness of immunity-boosting products (Ellis et al 2001).…”