Effect of uterine horn ligation on bone mass: an experimental study in rats

Rico, H.; Cuesta, C.; Cortés, J; Seco, C.; Monteagudo, M D; Hernández, E. R.

doi:10.1016/s0301-2115(01)00570-x

Cited by 1 publication

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Rico et al [33] reported that TL decreases the bone mass in the axial bones (spine and femur), which is similar to the bone mass loss in ovariectomy cases. Therefore, it can be concluded that TL may reduce estrogen.…”

Section: Discussionmentioning

confidence: 76%

Prooxidant-antioxidant balance and malondialdehyde over time in adult rats after tubal sterilization and vasectomy

Faramarzi

Seifi

Sadeghipour

et al. 2012

Clin Exp Reprod Med

View full text Add to dashboard Cite

ObjectiveSterilization (tubal sterilization and vasectomy) is a widely applied contraceptive method worldwide. Although most studies have described sterilization as a safe method, there are reports of tubal ligation (TL) and vasectomy complications. The aim of this study was to evaluate the effects of TL and vasectomy on the serum oxidative stress, specifically prooxidant-antioxidant balance (PAB) and malondialdehyde (MDA) levels, over time.MethodsMale and female rats were classified into vasectomy, sham-vasectomy, TL, and sham-TL groups, respectively. The PAB and MDA levels were measured on days 15 and 45 and months 3 and 6 after the intervention. For female rats, blood sampling was performed during the diestrous phase and estradiol and progesterone were also measured.ResultsSerum PAB and MDA increased after TL (p<0.05). Vasectomy increased serum MDA remarkably after 45 days, 3 months, and 6 months (p<0.05). After vasectomy, serum PAB also increased although not significantly. Serum estradiol and progesterone decreased remarkably in the TL group compared to the sham group (p<0.05).ConclusionBilateral TL and vasectomy both increase the serum oxidative stress; however the imbalance after TL was very noticeable. As for the TL, the reduction of serum estrogen levels can be involved in this imbalance. Complications followed by TL or vasectomy could be due to increased levels of oxidants. Thus, prescribing antioxidants during and or after surgery may be a solution.

show abstract

Section: Discussionmentioning

confidence: 76%