Effect of ultraviolet light on the hydrogenase of Proteus vulgaris

Purec, Ljerka; Krasna, Alvin I.

doi:10.1021/bi00841a008

Cited by 11 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reversal of CO inhibition by white light was also observed with intact cells and cell-free extracts of other bacteria [93][94][95][96][97] . Some of these early observations are ambiguous because some of the bacteria that were investigated, e.g.…”

Section: Early Functional Studies Of the Effect Of Light On Co-inhibited Hydrogenasesmentioning

confidence: 63%

Photochemistry and photoinhibition of the H-cluster of FeFe hydrogenases

Sensi

Baffert

Fourmond

et al. 2021

Sustainable Energy Fuels

View full text Add to dashboard Cite

show abstract

Section: Early Functional Studies Of the Effect Of Light On Co-inhibited Hydrogenasesmentioning

confidence: 63%

Photochemistry and photoinhibition of the H-cluster of FeFe hydrogenases

Sensi

Baffert

Fourmond

et al. 2021

Sustainable Energy Fuels

View full text Add to dashboard Cite

show abstract

“…Sympathetically mediated mitochondrial respiratory chain complex activation seems to be fundamental to thermogenesis induced by Meth in BAT, even though UCP1 and ATPases are induced by Meth regardless of intact nerve input. However, PKCdelta regulated processes, such as mitochondrial oxidative stress (Kohda and Gemba, 2005), which is highly active in BAT under sympathetic control (Prusiner et al, 1968a,b), may not have an important influence in temperature in Meth-injected animals, since KO animals showed the same hyperthermic profile as control animals (not shown).…”

Section: Discussionmentioning

confidence: 96%

“…Under basal conditions, respiration is coupled to phosphorylation in brown fat cells, and epinephrine stimulates a direct uncoupling action (Reed and Fain, 1968a,b) to produce heat (Prusiner et al, 1968a,b; Reed and Fain, 1968a,b). When activated by epinephrine, β3-adrenoceptors (β3-AR) in BAT mediate thermogenesis and induce lipolysis in WAT (Preitner et al, 1998; Collins and Surwit, 2001; Collins et al, 2001; Arch, 2002; Inokuma et al, 2005, 2006).…”

Section: Discussionmentioning

confidence: 99%

ROS and Sympathetically Mediated Mitochondria Activation in Brown Adipose Tissue Contribute to Methamphetamine-Induced Hyperthermia

Sanchez‐Alavez¹,

Conti²,

Wood³

et al. 2013

Front. Endocrinol.

View full text Add to dashboard Cite

Methamphetamine (Meth) abuse has been shown to induce alterations in mitochondrial function in the brain as well as to induce hyperthermia, which contributes to neurotoxicity and Meth-associated mortality. Brown adipose tissue (BAT), a thermogenic site known to be important in neonates, has recently regained importance since being identified in significant amounts and in correlation with metabolic balance in human adults. Given the high mitochondrial content of BAT and its role in thermogenesis, we aimed to investigate whether BAT plays any role in the development of Meth-induced hyperthermia. By ablating or denervating BAT, we identified a partial contribution of this organ to Meth-induced hyperthermia. BAT ablation decreased temperature by 0.5°C and reduced the length of hyperthermia by 1 h, compared to sham-operated controls. BAT denervation also affected the development of hyperthermia in correlation with decreased the expression of electron transport chain molecules, and increase on PCG1a levels, but without affecting Meth-induced uncoupling protein 1 upregulation. Furthermore, in isolated BAT cells in culture, Meth, but not Norepinephrine, induced H2O2 upregulation. In addition, we found that in vivo Reactive Oxygen Species (ROS) play a role in Meth hyperthermia. Thus, sympathetically mediated mitochondrial activation in the BAT and Meth-induced ROS are key components to the development of hyperthermia in Meth abuse.

show abstract

“…The photoreactivating enzyme which repairs pyrimidine dimers in DNA, a subject reviewed by Sutherland (1981), is known to be activated by visible light (300-600 nm). Purec and Krasna (1968), Galston (1950), Bernheim and Dixson (1928) and Hug and Hunter (1970) reported that the activities of, respectively, hydrogenase from Proteus vulgaris, indoleactic acid oxidase from peas, xanthine oxidase from fresh milk and urocanate hydratase from Pseudomonas putida can also be promoted by irradiation with UV or visible light. Also, a study on the nitrile hydratase of Rhodococcus sp.…”

Section: Introductionmentioning

confidence: 99%

PHOTOSENSITIVE PHENOMENA OF NITRILE HYDRATASE OF Rhodococcus sp. N‐771

Nagamune

Kurata

Hirata

et al. 1990

Photochem & Photobiology

View full text Add to dashboard Cite

Abstract— When the washed cells of Rhodococcus sp. N‐771 were incubated at 5°C in the dark under aerobic condition, their nitrile hydratase was inactivated after several days. Most of this activity was recovered by light irradiation. The speed of inactivation in the dark was affected by incubation temperature and amount of oxygen supply. Under anerobic conditions, however, this reversible dark inactivation was not observed; the photoirradiation of the cells irreversibly inactivated the initial cell activity by about 15%. The enzyme activity of the cell‐free extract of the inactivated cells can also be recovered when photoirradiated. This process did not require oxygen, and was not prevented by dialysis. However, the enzyme of the cell‐free extract could not be inactivated by dark, aerobic incubation nor by photoirradiation after dark anaerobic incubation.

show abstract

Effect of ultraviolet light on the hydrogenase of Proteus vulgaris

Cited by 11 publications

References 11 publications

Photochemistry and photoinhibition of the H-cluster of FeFe hydrogenases

Photochemistry and photoinhibition of the H-cluster of FeFe hydrogenases

ROS and Sympathetically Mediated Mitochondria Activation in Brown Adipose Tissue Contribute to Methamphetamine-Induced Hyperthermia

PHOTOSENSITIVE PHENOMENA OF NITRILE HYDRATASE OF Rhodococcus sp. N‐771

Contact Info

Product

Resources

About