Effect of type of secondary task on cued gait on people with idiopathic Parkinson′s disease

Chawla, Harsha; Walia, Shefali; Behari, Madhuri; Noohu, Majumi M.

doi:10.4103/0976-3147.127865

Cited by 13 publications

(6 citation statements)

References 21 publications

(40 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, Chawla et al suggested that FOG also involved the perception-cognition system that is mediated mainly by the frontal cortex. PD patients may recruit attention and cognition resources to compensate for the impairment in motor function to achieve a more normal gait, revealing that cognition-related damage to the frontal cortex is correlated with FOG (Chawla et al, 2014). Taken together, our findings reinforced that frontal gyrus dysfunction, especially in the MFG, is a key cortical pathogenic hub in PD-FOG patients.…”

Section: Discussionsupporting

confidence: 68%

Alterations in Degree Centrality and Functional Connectivity in Parkinson’s Disease Patients With Freezing of Gait: A Resting-State Functional Magnetic Resonance Imaging Study

Guo

Ren

et al. 2020

Front. Neurosci.

View full text Add to dashboard Cite

Objective: Freezing of gait (FOG) is a common disabling motor symptom in Parkinson's disease (PD), but the potential pathogenic mechanisms are still unclear. Methods: A total of 22 patients with PD with FOG (PD-FOG), 28 patients with PD without FOG (PD-nFOG), and 33 healthy controls (HCs) were recruited in this study. Degree centrality (DC)-a graph theory-based measurement of global connectivity at the voxel level by measuring the number of instantaneous functional connections between one region and the rest of the brain-can map brain hubs with high sensitivity, specificity, and reproducibility. DC was used to explore alterations in the centrality of PD-FOG correlated with brain node levels. PD-FOG cognitive network dysfunction was further revealed via a seed-based functional connectivity (FC) analysis. In addition, correlation analyses were carried out between clinical symptoms and acquired connectivity measurement. Results: Compared to the PD-nFOG group, the PD-FOG group showed remarkably increased DC values in the right middle frontal gyrus (RMFG). There were no significant differences in other gray matter regions. Importantly, the clinical severity of FOG was related to the mean DC values in the RMFG. This brain region served as a seed in secondary seed-based FC analysis, and we further found FC changes in the right precuneus, right inferior frontal gyrus, right superior frontal gyrus (SFG), and cerebellum. Conclusion: Increased RMFG activity and FC network alterations in the middle frontal cortex with the precuneus, inferior, and SFG, and the cerebellum may have great potential in brain dysfunction in PD with FOG.

show abstract

Section: Discussionsupporting

confidence: 68%

Alterations in Degree Centrality and Functional Connectivity in Parkinson’s Disease Patients With Freezing of Gait: A Resting-State Functional Magnetic Resonance Imaging Study

Guo

Ren

et al. 2020

Front. Neurosci.

View full text Add to dashboard Cite

show abstract

“…This approach proposes a unique assessment of CMI as well as allowing analysis of dual task interference from two cognitive tasks (cognitive-cognitive interference) or two motor tasks (motor-motor) performed simultaneously. Evidence suggests that the pairing of tasks is important in determining the effect of dual task interference, measured as task performance outcomes [ 7 – 9 ]; compare [ 10 ]. However, information processing creates a cognitive load regardless of the modality of task.…”

Section: Measuring Dual Task Performancementioning

confidence: 99%

Building a Framework for a Dual Task Taxonomy

McIsaac

Lamberg

Muratori

2015

BioMed Research International

167

135

View full text Add to dashboard Cite

The study of dual task interference has gained increasing attention in the literature for the past 35 years, with six MEDLINE citations in 1979 growing to 351 citations indexed in 2014 and a peak of 454 cited papers in 2013. Increasingly, researchers are examining dual task cost in individuals with pathology, including those with neurodegenerative diseases. While the influence of these papers has extended from the laboratory to the clinic, the field has evolved without clear definitions of commonly used terms and with extreme variations in experimental procedures. As a result, it is difficult to examine the interference literature as a single body of work. In this paper we present a new taxonomy for classifying cognitive-motor and motor-motor interference within the study of dual task behaviors that connects traditional concepts of learning and principles of motor control with current issues of multitasking analysis. As a first step in the process we provide an operational definition of dual task, distinguishing it from a complex single task. We present this new taxonomy, inclusive of both cognitive and motor modalities, as a working model; one that we hope will generate discussion and create a framework from which one can view previous studies and develop questions of interest.

show abstract

“…Previous studies have indicated, however, that performing two tasks simultaneously may negatively impact gait performance 1 – 3 . Dual task interference impacting gait performance has been observed not only in healthy subjects 4 – 6 , but also in subjects with neurological disorders 4 , 7 – 10 . In stroke individuals, reductions in speed, cadence, and stride length, as well as increases in stride time during cognitive-motor dual tasking have been reported 4 , 8 – 10 .…”

Section: Introductionmentioning

confidence: 99%

Cognitive and motor dual task gait training improve dual task gait performance after stroke - A randomized controlled pilot trial

Liu¹,

Yang²,

Tsai

et al. 2017

Sci Rep

View full text Add to dashboard Cite

This study investigated effects of cognitive and motor dual task gait training on dual task gait performance in stroke. Participants (n = 28) were randomly assigned to cognitive dual task gait training (CDTT), motor dual task gait training (MDTT), or conventional physical therapy (CPT) group. Participants in CDTT or MDTT group practiced the cognitive or motor tasks respectively during walking. Participants in CPT group received strengthening, balance, and gait training. The intervention was 30 min/session, 3 sessions/week for 4 weeks. Three test conditions to evaluate the training effects were single walking, walking while performing cognitive task (serial subtraction), and walking while performing motor task (tray-carrying). Parameters included gait speed, dual task cost of gait speed (DTC-speed), cadence, stride time, and stride length. After CDTT, cognitive-motor dual task gait performance (stride length and DTC-speed) was improved (p = 0.021; p = 0.015). After MDTT, motor dual task gait performance (gait speed, stride length, and DTC-speed) was improved (p = 0.008; p = 0.008; p = 0.008 respectively). It seems that CDTT improved cognitive dual task gait performance and MDTT improved motor dual task gait performance although such improvements did not reach significant group difference. Therefore, different types of dual task gait training can be adopted to enhance different dual task gait performance in stroke.

show abstract

Effect of type of secondary task on cued gait on people with idiopathic Parkinson′s disease

Cited by 13 publications

References 21 publications

Alterations in Degree Centrality and Functional Connectivity in Parkinson’s Disease Patients With Freezing of Gait: A Resting-State Functional Magnetic Resonance Imaging Study

Alterations in Degree Centrality and Functional Connectivity in Parkinson’s Disease Patients With Freezing of Gait: A Resting-State Functional Magnetic Resonance Imaging Study

Building a Framework for a Dual Task Taxonomy

Cognitive and motor dual task gait training improve dual task gait performance after stroke - A randomized controlled pilot trial

Contact Info

Product

Resources

About