Effect of two injections of non-adjuvanted influenza A H1N1pdm2009 vaccine in renal transplant recipients: INSERM C09-32 TRANSFLUVAC trial

Humoral, T-cell and B-cell immune responses to seasonal influenza vaccine in solid organ transplant recipients receiving anti-T cell therapies

“…However, characteristics of the cellular immune response to influenza vaccine in immunocompromised patients, such in SOT recipients [4,23,37,38] are not widely reported. Because of lower CD4+ T-cell counts, we expected lower influenza specific T-cell mediated responses in patients receiving ATG, but this was not observed in our study.…”

B-Sides Serologic Markers of Immunogenicity in Kidney Transplanted Patients

“…Contradictory data have been reported for vaccines against measles, tetanus, and pneumococcus (19Y22). Data on influenza vaccination are also controversial because results have indicated both normal and compromised immune responses to influenza vaccination in Tps (11,16). Furthermore, data on safety (15,16) of influenza vaccination in SOT recipients seem to be conflicting.…”

Immunization in End‐Stage Renal Disease: Opportunity to Improve Outcomes

“…There are conflicting data on response rates to vaccination (81)(82)(83)(84)(85)(86)(87)(88)(89). Response rates to influenza vaccination may be similar to (84,86,90) or lower (85,87) than those in the general population (81,82,91), although the antibody response to influenza vaccination is generally adequate (81,83,86,88,90,92).…”

“…Seroconversion rates to H1N1 vaccine in hemodialysis patients may be inadequate for single-dose vaccine (96). Two doses of H1N1 vaccine increased response rates in renal transplant patients (89). A booster dose of vaccine improved response rates in the elderly (97), and in hemodialysis patients (98) as did a high-dose influenza vaccination (99).…”