Effect of Triclosan‐Coated Sutures on the Incidence of Surgical Wound Infection After Lower Limb Revascularization Surgery: A Randomized Controlled Trial

Abstract

The use of triclosan-coated sutures does not reduce the incidence of SWI after lower limb vascular surgery.

Surgical wound infections after peripheral vascular surgery

“…The study showed that triclosan-coated sutures do not reduce the risk of SWI (13). Another randomized trial with 374 patients reported that legwound closure with triclosan-coated sutures does reduce the SWI rate in cAbg patients after open vein harvesting (62).…”

“…Furthermore, obesity has increased the risk of SWI after peripheral artery surgery in other studies with smaller number of patients with an OR varying between 1.7 and 6.08 (11,13,23,25,39). In addition, morbid obesity (body mass index (bmI) ≥ 40 kg/m 2 ) has been found to be an independent risk factor for SWI after open aortic aneurysm repair with an OR of 2.6 (16).…”

“…In prospective studies with the number of patients ranging from 69 to 561, the incidence of SWI was found to be between 3.5% and 32% (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13).…”

“…The other causative bacteria are as follows: Staphylococcus epidermidis 17%-24%, Streptococcus 19%, Pseudomonas 3%-20%, Enterococcus 6%-21%, Escherichia coli 2%-9%, and Enterobacter 3%-9% (11-13, 25, 44, 45-46). cultures taken from wound with clinical signs of infection do not exhibit bacterial growth in 10%-17% of the cases (12,13).…”

Prävention postoperativer Wundinfektionen

“…Es könnte deshalb mit seiner Verwendung zur Reduktion des SSI-Risikos kommen. Die diesbezügliche Studienlage ist uneinheitlich [192][193][194][195][196][197][198][199][200][201]. Die WHO empfiehlt die Verwendung unabhängig von der Art der Operation [40], das CDC in der Viszeralchirurgie [202].…”