Effect of treatment at different time intervals for traumatic tympanic membrane perforation on the closure

Abstract

In the group treated with the gelatin sponge patch technique, the patients sought medical treatment at different time intervals since the injury. Accordingly, the outcome of the treatment varied in terms of the perforation closure rates achieved in different patients in this group. The respective perforation closure rates were 100%, 100%, 96%, 94%, and 89% in accordance with the time interval at which the patients were treated since the injury. The results were not significantly different when compared by statistical analysis (p > 0.05); the mean closure times in each of the different sets of cases in this group were calculated and the following values were reported: 7.1 ± 2.3, 8.2 ± 1.6, 8.7 ± 1.2, 9.2 ± 3.1, and 10.7 ± 3.9 days. On the other hand, in the edge approximation plus gelfoam patching group, the perforation closure rates were 100%, 97%, 96%, 97%, and 94%, respectively. This was in accordance with the time elapsed since the injury for the patients who visited the hospital on different days. Statistical analysis confirmed that the perforation closure rates for the different cases of this group did not have any significant difference (p > 0.05); the mean closure times were 7.6 ± 1.9, 7.9 ± 2.2, 9.2 ± 2.8, 8.5 ± 3.6, and 11.2 ± 4.1 days, respectively, indicating that differences were not significant even in terms of mean closure rates for the different cases of this group (p > 0.05).

A prospective study evaluating spontaneous healing of aetiology, size and type‐different groups of traumatic tympanic membrane perforation

“…Accelerated healing of fresh wet traumatic perforations without any increased risk of middle ear infection suggests that keeping the local environment in the perforated and healing eardrum wet or moist by means of applying aseptic ointment 19 or various exogenous growth factors (e.g. epidermal growth factor 24 and fibroblastic growth factors 25 ) may be considered an effective approach to promote perforation closure, particularly in case of malleus injury.…”

Traumatic perforations of the tympanic membrane: immediate clinical recovery with the use of bacterial cellulose film

“…Traumatic perforation of the TM can heal spontaneously in 70–90% of cases, but the duration of the process until the complete closure may be long and sometimes take one month or longer. 3 Surgical management, such as tympanoplasty or myringoplasty to close the tympanic perforation is more invasive and costly and, therefore, is an option reserved for cases in which there was no spontaneous resolution of the condition. Thus, for these reasons, the primary treatment is a conservative one.…”

Early Paper Patching Versus Observation in Patients With Traumatic Eardrum Perforations

“…5 A great diversity exists regarding the philosophy of treating traumatic TMPs and associated injuries. [9][10][11] On the basis of this background, in this retrospective clinical study, we aimed to compare the outcomes of 2 different approaches for TMPs, conservative management and paper patching, to investigate the therapeutic role of the patching procedure in acute cases with eardrum ruptures. [6][7][8] Among them, paper patching has many advantages, because the use of cigarette paper is cost-effective and the material is readily available.…”