Effect of Trabeculectomy on Visual Field in Progressive Normal-Tension Glaucoma

Daugeliene, Lina; Yamamoto, Tetsuya; Kitazawa, Yoshiaki

doi:10.1016/s0021-5155(98)00013-6

Cited by 36 publications

(24 citation statements)

References 20 publications

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“…Adhering to a goal of a low IOP may result in a higher incidence of disastrous postoperative complications and lower quality of life. 6,18 Another significant finding is that our patients had good quality of vision after combined cataract and glaucoma surgery. Considering the more important outcomes, such as the quality of vision, quality of activities of daily living, good visual acuity, less deterioration in visual fields, and less need for maintenance (ie, fewer visits to an ophthalmologist and fewer postoperative complications and medications), phacoviscocanalostomy may be a good therapeutic option for elderly patients.…”

Section: Discussionmentioning

confidence: 57%

“…2,17 Conventional filtering surgery remains the mainstay of surgical therapies for managing NTG refractory to medication. [6][7][8][9][18][19][20][21] Trabeculectomy can reduce IOP significantly; however, the surgery may be associated with vision-threatening complications that reduce the quality of vision. 6,8,9 These include bleb leaks, hypotony, a flat anterior chamber, choroidal detachment, and endophthalmitis.…”

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confidence: 99%

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Phacoviscocanalostomy versus cataract surgery only in patients with coexisting normal-tension glaucoma: Midterm outcomes

Shoji¹,

Tanito²,

Takahashi³

et al. 2007

Journal of Cataract and Refractive Surgery

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Section: Discussionmentioning

confidence: 57%

mentioning

confidence: 99%

Phacoviscocanalostomy versus cataract surgery only in patients with coexisting normal-tension glaucoma: Midterm outcomes

Shoji¹,

Tanito²,

Takahashi³

et al. 2007

Journal of Cataract and Refractive Surgery

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“…Kalziumkanalblocker scheinen einen positiven Effekt auf Patienten zu haben, die bereits eine erfolgreiche Trabekulektomie hatten, indem sie den Blutfluss im Sehnerven verbessern [60,61,62]. Netland et al [63] fanden in einer Studie mit einer Nachbeobachtungszeit von 3 1/2 Jahren, dass weniger Patienten unter Kalziumkanalblockern eine Progression hatten als in der Gruppe ohne Kalziumkanalblocker.…”

Section: Erkrankungen Für Die Ein Kausaler Zusammenhang Zum Normaldrunclassified

Aktuelle Aspekte zum Management des Normaldruckglaukoms

et al. 2015

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In a considerable proportion of glaucoma patients (25-50 %) the intraocular pressure (IOP) is not elevated higher than 22 mmHg at first diagnosis and during subsequent follow-up controls. Although the IOP level remains in the low range < 22 mmHg, progression of glaucoma can still occur. A multitude of different factors are assumed to be involved in glaucoma progression, such as very low nocturnal diastolic blood pressure values, a low mean ocular perfusion pressure, extensive fluctuations in perfusion (e.g. in cases of vascular dysregulation), an increased vulnerability of the optic nerve support structures, an increased translaminar pressure gradient and various underlying systemic diseases. The most important evidence-based aspect of treatment in normal tension glaucoma is pharmaceutical or surgical reduction of the IOP by 30 % or more in comparison to the initial pressure level. Vascular and neuroprotective concepts of treatment for normal tension glaucoma have been strongly advocated and the object of experimental and clinical studies. As yet a clear clinical benefit has not been proven by large prospective randomized studies.

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“…Besides intraocular pressure (IOP), mainly an altered ocular perfusion has been suggested to be a risk factor for this potentially blinding disease, especially when IOP appears to have been normal. There are patients with glaucomatous optic neuropathy but without increased IOP (normal-tension glaucoma) whose disease process is markedly slower down by the traditional intervention of IOP reduction [2, 3, 4]. In addition, despite measured IOP values within the statistical limits of normal range, many patients with normal-tension glaucoma show a more marked deterioration of the visual field in the eye with the higher IOP [5, 6, 7], although such a relationship was not confirmed in all studies [8].…”

Section: Introductionmentioning

confidence: 99%

“…Another study suggested that patients with normal-tension glaucoma with a mean preoperative IOP higher than 15 mm Hg benefit most from surgical IOP lowering [4]. …”

Section: Introductionmentioning

confidence: 99%

Asymmetry in Intraocular Pressure and Retinal Nerve Fiber Layer Thickness in Normal-Tension Glaucoma

Gugleta

Orgül²

1999

Ophthalmologica

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The etiology of glaucoma is most probably multifactorial. This study intended to investigate the asymmetry in intraocular pressure (IOP) and that in retinal nerve fiber layer (RNFL) thickness in normal-tension glaucoma patients. Two diurnal tension curves, obtained within 3 months and counting at least five IOP readings each, including an early morning IOP measurement upon awaking, were obtained in 15 normal-tension glaucoma patients. None of the patients received IOP-lowering therapy. IOP asymmetry was present in at least three readings and was always in the same direction. The optic nerve was imaged in both eyes in each patient by means of confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph). The interocular difference in RNFL thickness and the RNFL cross-sectional area were correlated with the interocular difference in IOP by means of Spearman’s rank correlation factor. Nine female and 6 male normal-tension glaucoma patients (mean ± SD age was 62.4 ± 16.9 years) were included in this study. Interocular IOP asymmetry varied between 0.30 and 4 mm Hg. Strong negative correlations were found between interocular asymmetry in IOP and interocular asymmetry in RNFL thickness asymmetry (R = –0.652, p = 0.0083) and interocular asymmetry in RNFL cross-sectional area (R = –0.702, p = 0.0034). The present results demonstrate for the first time a more marked thinning of the neuroretinal nerve fiber layer in the eye with the higher IOP in normal-tension glaucoma patients.

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Effect of Trabeculectomy on Visual Field in Progressive Normal-Tension Glaucoma

Cited by 36 publications

References 20 publications

Phacoviscocanalostomy versus cataract surgery only in patients with coexisting normal-tension glaucoma: Midterm outcomes

Phacoviscocanalostomy versus cataract surgery only in patients with coexisting normal-tension glaucoma: Midterm outcomes

Aktuelle Aspekte zum Management des Normaldruckglaukoms

Asymmetry in Intraocular Pressure and Retinal Nerve Fiber Layer Thickness in Normal-Tension Glaucoma

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