Effect of TiO₂nanoparticles on the performance of polyphenylsulfone biomaterial for orthopaedic implants

Abstract

Nanocomposites of biocompatible polyphenylsulfone (PPSU) and titanium dioxide (TiO 2 ) nanoparticles have been prepared via ultrasonication and solution casting. Their structure, surface morphology, water uptake, thermal, mechanical, tribological and antibacterial properties have been investigated in detail.FT-IR analysis revealed the existence of strong hydrogen bonding interactions between the sulfone group of PPSU and the hydroxyl moieties of the nanoparticles, which were homogenously dispersed within the matrix without adding coupling agents. The incorporation of TiO 2 reduced the water absorption and increased the thermal stability of the polymer under both inert and oxidative conditions. Furthermore, the nanocomposites exhibited greatly enhanced mechanical performance (storage and Young's moduli, tensile strength and toughness, glass transition and heat distortion temperature) compared to neat PPSU, confirming the formation of a strong nanofiller-matrix interface necessary for an efficient load transfer. Moreover, their tensile properties were retained after exposure to several cycles of steam sterilization or to simulated body fluid (SBF) at physiological temperature. Outstanding improvements in the tribological performance under both dry and SBF conditions were also attained, demonstrating the suitability of these nanoparticles for providing wear resistance to the matrix. The nanocomposites exhibited inhibition against both Gram-positive and Gram-negative bacteria with and without UV illumination, which was progressively enhanced with increasing TiO 2 loading. These biomaterials are very promising for use in biomedical applications like orthopaedic and trauma implants.

Polyphenylsulfone-based solvent resistant nanofiltration (SRNF) membrane incorporated with copper-1,3,5-benzenetricarboxylate (Cu-BTC) nanoparticles for methanol separation

“…4(b) and (c). 39 Results show most of the peaks appeared in PPSU could also be found in the PPSU/0.8Cu-BTC (Fig. 4(b), the PPSU shows absorption peaks at 1320 and 1151 cm À1 which can be ascribed to the asymmetrical and symmetrical stretching vibrations of the SO 2 group, respectively.…”

Evaluation of PLA nanocomposite films on physicochemical and microbiological properties of refrigerated cottage cheese

“…The nanofiller content and state of dispersion are very important factors determining the antimicrobial ability of nanocomposite packaging films. Díez‐Pascual and Díez‐Vicente () reported that the minimum TiO 2 content required for effective microbial growth inhibition was 3.0 wt %. On the other hand, the homogeneous nanoparticle distribution in the nanocomposites was related to the strong microbial inactivation.…”

Effect of etching on the composition and structure of anodic spark deposition films on titanium

“…This activity towards a multidrug resistant bacterium was observed to be close to the behaviour of similar anodic layers modified with the addition of silver [11]. One mechanism was envisioned as responsible for this unexpected antibacterial activity, that is, the formation of reactive oxygen species due to non-stoichiometry of the oxide film, and particularly to a large content of Ti 3+ species as a result of oxygen vacancies: this, together with other features related to TiO 2 nanoparticles rather than to anodic surfaces, was already proved to be a possible source of antimicrobial effects [20,21].…”