Effect of three different anti-mycotoxin additives on broiler chickens exposed to aflatoxin B1

Oliveira, AA; Keller, KM; Deveza, MV; Keller, Laura; Dias, EO; Martini-Santos, BJ; Leitao, Dfgm; Cavaglieri, L. R.; Rosa, Carlos Alberto da Rocha

doi:10.4067/s0301-732x2015000200008

Cited by 9 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The Saccharomyces cerevisiae yeast cell wall (YCW) is an organic substance that has been used as an adsorbent of mycotoxins in animal feed (Santin et al 2003). Positive in vitro results match the results of in vivo studies, where YCW was able to minimize the toxicity of aflatoxins, demonstrating the beneficial effects of its addition to broiler feed (Celyk et al 2003;Santin et al 2003;Oliveira et al 2015).…”

Section: Original Papermentioning

confidence: 70%

Broiler chick performance using Saccharomyces cerevisiae yeast cell wall as an anti-mycotoxin additive

Santos¹,

Oliveira²,

Lima³

et al. 2021

CZECH J ANIM SCI

View full text Add to dashboard Cite

The objective of this study was to evaluate the effects of using the Saccharomyces cerevisiae yeast cell wall (YCW) as an aflatoxin B1 (AFB1) adsorbent in broiler chicken feed on performance and carcass characteristics. The present study used a randomized complete block with four treatments in a 2 (with or without AFB1) × 2 (with or without YCW) factorial design. No interaction effect (P > 0.05) between AFB1 and YCW was found on the studied performance variables. The addition of YCW to the diets stimulated the feed intake of chickens during 1–21 days of age. However, YCW did not significantly increase (P > 0.05) weight gain nor did it change feed conversion. The presence of AFB1 in the diet did not affect (P > 0.05) performance parameters. The addition of YCW to the feed containing AFB1 significantly increased (P < 0.05) the post-fasting live weight (781.12 g), chilled carcass weight (554.41 g), and leg weight (163.34 g) compared to feed without AFB1 and YCW (764.84 g; 533.41 g; 161.88 g), feed with only YCW (764.22 g; 546.87 g; 159.34 g), and feed with only AFB1 (735.41 g; 510.56 g; 152.75 g). In conclusion, YCW effectively reduced some of the deleterious effects of AFB1 in broilers.

show abstract

Section: Original Papermentioning

confidence: 70%

Broiler chick performance using Saccharomyces cerevisiae yeast cell wall as an anti-mycotoxin additive

Santos¹,

Oliveira²,

Lima³

et al. 2021

CZECH J ANIM SCI

View full text Add to dashboard Cite

show abstract

“…• Oliveira et al (2015) added anti-mycotoxin additives based on SCE (0.2%) to AFB1-CT (1 ppm) broiler diet for 21 d. The addition of two different kinds of SCE (0.2%) could reverse such effects. These are the first data reported from Brazil anti-mycotoxin additives with preliminary isothermal analysis.…”

Section: Brazilmentioning

confidence: 99%

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Oguz¹

2016

EurasianJVetSci

View full text Add to dashboard Cite

show abstract

“…Therefore, YCW could be an alternative over conventional adsorbent materials to bind a wide variety of mycotoxins (6), without reducing nutrient bioavailability or causing negative environmental impacts. While many studies have been conducted to show that YCW can improve broiler performance and intestinal health when challenged with aflatoxins alone or in combination with pathogens (7,8), just a few studies have looked into the pathways that lead to the formation of complexes involving mycotoxins and YCW components, where some chemical structures such as (1→ 3)β-D-glucan or (1→ 6)-β-D-glucan play a significant role during the binding process (9)(10)(11). Currently, there is a lack of general…”

Section: Introductionmentioning

confidence: 99%

Mitigation of AFB1-Related Toxic Damage to the Intestinal Epithelium in Broiler Chickens Consumed a Yeast Cell Wall Fraction

et al. 2021

View full text Add to dashboard Cite

In vivo experiments were conducted to evaluate the effectiveness of a yeast cell wall fraction (YCW) to reduce the negative impact of aflatoxin B1 (AFB1) to the intestinal epithelium in broiler chickens. Zeta potential (ζ-potential), point of zero charge (pHpzc), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) techniques were used to characterize the YCW. Two hundred one-day-old male Ross 308 broiler chickens were randomly allocated into four treatments: (1) control, chickens fed an AFB1-free diet; (2) AF, chickens feed an AFB1-contaminated diet (500 ng AFB1/g); (3) YCW, chickens fed an AFB1-free diet + 0.05% YCW; and (4) AF + YCW, chickens fed an AFB1-contaminated diet (500 ng AFB1/g) + 0.05% YCW. At the end of the 21-day feeding period, fluorescein isothiocyanate dextran (FITC-d) was administered to chicks by oral gavage to evaluate gastrointestinal leakage. Blood and duodenum samples were collected to assess serum biochemistry and histomorphology, respectively. Compared to the control group, chicks of the AF group significantly diminished weight gain (WG) and average daily feed intake (ADFI), and increased feed conversion ratio (FCR), mortality rate (MR), and intestinal lesion scores (p < 0.05). Alterations in some serum biochemical parameters, and damage to the intestinal integrity were also evident in the AF-intoxicated birds. YCW supplementation improved WG and FCR and increased villus height, villus area, crypt depth, and the number of goblet cells in villi. The effects of YCW on growth performance were not significant in chicks of the AF + YCW group; however, the treatment decreased MR and significantly ameliorated some biochemical and histomorphological alterations. The beneficial effect of YCW was more evident in promoting gut health since chickens of the AF + YCW group presented a significant reduction in serum FITC-d concentration. This positive effect was mainly related to the changes in negative charges of YCW due to changes in pH, the net negative surface charge above the pHpzc, the higher quantities of negative charged functional groups on the YCW surface, and its ability to form large aggregates. From these results, it can be concluded that YCW at low supplementation level can partially protect broilers' intestinal health from chronic exposure to AFB1.

show abstract

Effect of three different anti-mycotoxin additives on broiler chickens exposed to aflatoxin B1

Cited by 9 publications

References 15 publications

Broiler chick performance using Saccharomyces cerevisiae yeast cell wall as an anti-mycotoxin additive

Broiler chick performance using Saccharomyces cerevisiae yeast cell wall as an anti-mycotoxin additive

Meta analytic study on detoxification of aflatoxin in poultry feed: An update

Mitigation of AFB1-Related Toxic Damage to the Intestinal Epithelium in Broiler Chickens Consumed a Yeast Cell Wall Fraction

Contact Info

Product

Resources

About