Effect of therapeutic ultrasound and diathermy on oxidant–antioxidant balance in dogs suffering from hind quarter weakness

Abstract

The present study was conducted to evaluate the erythrocytic oxidantÁantioxidant balance in dogs suffering from hind quarter weakness (HQW) and treated with conventional drug therapy (CDT, n 08) alone and in combination with therapeutic ultrasound (US, n 08) and shortwave diathermy (SWD, n 08). A further eight healthy dogs were used as controls. For oxidant level, Lipid Peroxidation (LPO) and antioxidant levels Reduced Glutathione (GSH), Superoxide Dismutase (SOD) and Catalase (CAT) were evaluated in erythrocyte before (day 0) and after 3, 7, 14 and 28 days of therapy. In dogs with HQW, LPO in terms of Malondialdehyde (MDA) production, was found significantly (P B0.05) increased compared to a healthy control on day 0. Thereafter, a significant (PB0.05) decrease in the level of LPO was noticed. Amongst antioxidant enzymes, activities of GSH and CAT decreased significantly (PB0.05) whereas, the level of SOD increased significantly (PB0.05) until day 28 post treatment. Studies revealed that SWD and therapeutic ultrasound in conjunction with CDT can be used to counter free radical-mediated oxidative cell injury, induced by HQW in dogs. However, SWD proved to be better in minimizing excess free radicals production and activating antioxidant defense system as compared to therapeutic ultrasound.

Systematic Review of Complementary and Alternative Veterinary Medicine in Sport and Companion Animals: Therapeutic Ultrasound

“…Randomized controlled trial. The results of an RCT involving 24 dogs with hindquarter weakness (HQW) have been reported in two separate articles [ 28 , 29 ]. The risk of bias was assessed to be moderate.…”

A Systematic Review of Complementary and Alternative Veterinary Medicine in Sport and Companion Animals: Electrotherapy

“…Two studies on short-wave diathermy fulfilled the inclusion criteria for this review, and both were conducted on dogs [4,45] (Table 9).…”

“…Diathermy was reported to be beneficial in reducing antioxidant stress [45], and to lead to better recovery in dogs with hindquarter weakness [4].…”

Design of an ultrasonic physiotherapy system with pulse wave feedback control

“…Ultrasonic hyperthermia relies on the conversion of ultrasonic mechanical energy into thermal energy in biological tissues. Higher temperature causes damage to lesion tissue, while a lower amount of energy absorption promotes the rehabilitation of lesion tissue [10]. The low-intensity pulsed ultrasound (LIPUS) used in this rehabilitation technology transfers energy at an intensity less than 3 W/cm 2 , which is not sufficient to cause a thermal effect, so it avoids the adverse reactions associated with traditional ultrasound treatment.…”

“…The ultrasonic control signal is modulated to the processed pulse wave as the carrier signal, which is shown in Eq. (10), where the modulated waveform is F (t) and the pulse wave is m(t):…”