Effect of the solid–liquid extraction solvent on the phenolic content and antioxidant activity of three species of <i>Stevia</i> leaves

Medina-Medrano, José Roberto; Torres-Contreras, Josselin Estefani; Valiente-Banuet, Juan I.; Mares-Quiñones, María Daniela; Vázquez-Sánchez, Monserrat; Álvarez-Bernal, Dioselina

doi:10.1080/01496395.2018.1546741

Cited by 12 publications

(7 citation statements)

References 31 publications

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“…The results showed a wide variation in the recovery of total polyphenols, flavonoids, and flavonols content in the different stevia extracts. It could be due to the solubility of the phenolic compounds in the extraction solvent used [ 36 ]. Based on our data, the ethyl acetate extract indicates the highest quantity of bioactive compounds.…”

Section: Total Phenolics Flavonoids and Flavonols Contentmentioning

confidence: 82%

Chemical composition, antioxidant, anticholinesterase, and alpha-glucosidase activity of Stevia rebaudiana Bertoni extracts cultivated in Algeria

et al. 2023

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MJqh-H-1eF8_MiWzthapyIDPZUrG-9DcTP2nu627Q97LLzCqOtr-QCmU0n1vvUfE3gv80BFspHYRh3zj5ohzwFFGhVPm1k9kJ4_ef4GPzoUO9JLQmNBtxtU6rYgn 1/12 1. Please con irm if the author names are presented accurately and in the correct sequence. Author 2 Given name: [Abdenour Ait] Last name [Ouazzou]. Also, kindly con irm the details in the metadata are correct. 2. Please check and con irm that the authors and their respective af iliations have been correctly identi ied and amend if necessary. 3. Please provide complete details for reference 37. 4. Please provide a de inition for the signi icance of [bold] in the table 1, 4. 5. As References [11, 41] and [35, 36] were same, we have deleted the duplicate references and renumbered accordingly. Please check and con irm.

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Section: Total Phenolics Flavonoids and Flavonols Contentmentioning

confidence: 82%

Chemical composition, antioxidant, anticholinesterase, and alpha-glucosidase activity of Stevia rebaudiana Bertoni extracts cultivated in Algeria

et al. 2023

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“…Medina-Medrano et al 59 have found that SLE solvent combination ethanol–water can greatly influence the concentration of phenolic content extracted from leaves of Stevia origanoides , Stevia ovata, and Stevia viscida . It is found that hydrochloric acid hydrolysis is of similar effectiveness to, but much cheaper than, the enzymatic method.…”

Section: Extraction Methods Of Phenolic Compoundsmentioning

confidence: 99%

A Brief Review of Phenolic Compounds Identified from Plants: Their Extraction, Analysis, and Biological Activity

Zhang

Cai

Cheng

et al. 2022

Natural Product Communications

119

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Phenolic compounds are the most abundant secondary metabolites in plants, showing a wide range of distinct biological activities, have received more and more attention in recent years. This review aims to gather and systematize available information on the phenolic compounds from plants by discussing different types of phenolic compounds, extraction, and analysis methods, with an emphasis on their potential biological activities. The research direction and problems that should be paid attention to in the future are also put forward to provide some references for the further study of phenolic compounds.

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“…The total flavonoid content (TFC) of the crude extract and its fractions was estimated using a modified spectrophotometric method (Medina‐Medrano et al, 2019 ). Briefly, the extracts (2 mL) were mixed with 5% AlCl 3 (0.5 mL) and 1 M potassium acetate solution (0.5 mL).…”

Section: Methodsmentioning

confidence: 99%

Fractionation, identification of chemical constituents, and biological properties of cashew (Anacardium occidentale L.) leaf extracts

Pham,

Truong,

Tran

et al. 2023

Food Science & Nutrition

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The current study aimed to identify the chemical constituents and bioactivities of the crude ethanolic extract (CEE) and its fractions (ethyl acetate (EAF), hexane (HEF), and aqueous (AEF)) from leaves of cashew (Anacardium occidentale L.) grown in Vietnam. A total of 31 compounds which belong to alkanes, hydrocarbons, iodine, terpenoids, phenolics, and flavonoids were determined by a gas chromatography–mass spectrometry (GC–MS) analysis, with bis(2‐ethylhexyl) phthalate being the most prevailing compound. The highest total phenolic and flavonoid contents were obtained in the EAF, followed by HEF, CEE, and AQF. All samples showed promising in vitro antibacterial activity, enzyme inhibition, and anticancer activity. Among the samples tested, the EAF exhibited the highest enzyme inhibition activity against α‐amylase and α‐glucosidase (IC50 values of 51.24 μg/mL and 99.29 μg/mL, respectively), cytotoxicity activity against HeLa cells (IC50 value of 79.49 μg/mL), and antibacterial activity against Bacillus subtilis and Escherichia coli with MIC values of 5 mg/mL and 2.5 mg/mL, respectively. These findings suggest that the leaves of A. occidentale cultivated in Vietnam are a promising source of bioactive components and that EAF is a promising bioactive material warranting further pharmaceutical investigation.

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Effect of the solid–liquid extraction solvent on the phenolic content and antioxidant activity of three species of Stevia leaves

Cited by 12 publications

References 31 publications

Chemical composition, antioxidant, anticholinesterase, and alpha-glucosidase activity of Stevia rebaudiana Bertoni extracts cultivated in Algeria

Chemical composition, antioxidant, anticholinesterase, and alpha-glucosidase activity of Stevia rebaudiana Bertoni extracts cultivated in Algeria

A Brief Review of Phenolic Compounds Identified from Plants: Their Extraction, Analysis, and Biological Activity

Fractionation, identification of chemical constituents, and biological properties of cashew (Anacardium occidentale L.) leaf extracts

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